17-994-982

CD278 (ICOS) Monoclonal Antibody (C398.4A), APC, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 17-994-982-Each-of-1 In Stock ₹ 25,098.00

17-994-982 - Each of 1

₹ 25,098.00

In Stock

Quantity

1

Base Price: ₹ 25,098.00

GST (18%): ₹ 4,517.64

Total Price: ₹ 29,615.64

Antigen

CD278 (ICOS)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9R1T7, Q9WVS0

Gene Symbols

ICOS

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54167, 64545, 705788

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

C398.4A

Conjugate

APC

Gene

ICOS

Gene Alias

Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115

Host Species

Armenian Hamster

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat, Rhesus Monkey

Product Type

Antibody

Isotype

IgG

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Description

  • Description: The C398.4A monoclonal antibody reacts with ICOS (Inducible Costimulatory molecule), also known as H4/CRP-1/AILIM, and cross-reacts with mouse and rat ICOS
  • ICOS is a T cell specific activation molecule and a third member of the CD28/CTLA-4 family
  • A dimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response
  • ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1, is thought to play a protective role in inflammatory autoimmune diseases and be involved in the development of Th2 cells
  • C398.4A is reported to display strong costimulation of proliferation of T cell clones, intermediate costimulation on activated T cells, and weak costimulation on fresh resting T cells
  • It is a good costimulator of IL-10 production especially from pre-activated cells that express high level of H4/ICOS
  • The epitope recognized by C398.4A is different from that bound by the ICOSL (i.e., C398.4A does not block binding of ICOSL)
  • Applications Reported: This C398.4A antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This C398.4A antibody has been tested by flow cytometric analysis of Con A-stimulated mouse splenocytes
  • This can be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • CD278 (ICOS) Monoclonal antibody specifically detects CD278 (ICOS) in Mouse, Rat, Rhesus Monkey samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

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Fischer Scientific

17-994-982

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Antigen:
CD278 (ICOS)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9R1T7, Q9WVS0

Gene Symbols:
ICOS

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54167, 64545, 705788

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
C398.4A

Conjugate:
APC

Gene:
ICOS

Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115

Host Species:
Armenian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG

Img

Invitrogen

17-995-242

--


Antigen:
HLA-DR

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01903, P01911, P04233, P13762, P18470, P79483, Q30154

Gene Symbols:
CD74, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102131412, 3122, 3123, 3125, 3126, 3127, 474860, 479329, 710820, 972

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
L243

Conjugate:
APC

Gene:
HLA-DRB4

Gene Alias:
AI323765, BLA-DRB3, BOLA-DRA, BoLA-DR-alpha, BoLA-DRB, BOLA-DRB3, BoLA-DRB3 protein, BoLA-DRB3.2, Bota-DRB01, Bota-DRB02, Bota-DRB04, Bota-DRB07, Bota-DRB21, Bota-DRB22, bovine leukocyte antigen, Cd74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 molecule, Cd74 molecule, major histocompatibility complex, class II invariant chain, class II-associated invariant chain peptide, CLIP, Clone P2-beta-3, DASS-397D15.1, DHLAG, dinucleotide microsatellite, DLA class II histocompatibility antigen, DR-1 beta chain, DLA DRBB1 beta chain, DLA-DR beta, DLA-DRB1, DLA-DRBB1, DR beta-5, DR beta-chain antigen binding domain, DR-16, DR2-beta-2, DR4, DR-4, DR7, DR9, DR-9, DRB, DRB1, DRB1 transplantation antigen, DRB3, DRB4, DRBB1, DR-beta chain, DR-beta chain MHC class II, DRw10, Dw2, DW2.2/DR2.2, E-alpha-f, FLJ51114, FLJ75017, FLJ76359, gamma chain of class II antigens, H-2 class II histocompatibility antigen gamma chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2Ea, H2-Ea, H2-Ea-ps, H2-IE-alpha, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility antigen HLA-DR alpha, histocompatibility complex, class II, DR beta 3, histocompatibility: class II antigens, gamma chain of, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DR beta 4 chain, HLA class II histocompatibility antigen, DR beta 5 chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA class II histocompatibility antigen, DR-5 beta chain, HLA class II histocompatibility antigen, DRB1-15 beta chain, HLA class II histocompatibility antigen, DRB1-16 beta chain, HLA class II histocompatibility antigen, DRB1-3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA class II histocompatibility antigen, DRB1-9 beta chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR1B, HLA-DR3B, HLA-DR4B, HLA-DRA, HLA-DRA1, HLA-DRB, HLA-DRB1, HLA-DRB2, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DR-gamma, human leucocyte antigen DRB1, human leucocyte antigen DRB3, human leucocyte antigen DRB4, human leucocyte antigen DRB5, ia antigen-associated invariant chain, Ia3, Ia-3, Ia-associated invariant chain, Ia-GAMMA, I-E alpha MHC class II, I-Ealpha, II, integral membrane glycoprotein, invariant gamma chain, invariant polypeptide of major histocompatibility complex, class II antigen-associated, INVG34, LA-DRB, leukocyte antigen, leukocyte antigen class II, leukocyte antigen DRB3, lymphocyte antigen DRB1, major histocompatibility complex class II DR-beta chain, major histocompatibility complex, class II, DR alpha, major histocompatibility complex, class II, DR alpha precursor, major histocompatibility complex, class II, DR beta 1, major histocompatibility complex, class II, DR beta 3, major histocompatibility complex, class II, DR beta 4, major histocompatibility complex, class II, DR beta 4 precursor, major histocompatibility complex, class II, DR beta 5, major histocompatibility complex, class II, DRB3, MHC cell surface glycoprotein, MHC class I antigen, MHC class II antigen, MHC class II antigen beta chain, MHC class II antigen BoLA-DRB3, MHC class II antigen DR beta 3 chain, MHC class II antigen DRA, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*9, MHC class II antigen DRB3, MHC class II antigen DRB4, MHC class II antigen DRB5, MHC class II antigen E alpha, MHC class II antigen HLA-DR-beta, MHC class II DLA DRB1 beta chain, MHC class II DLA-DRB, MHC class II DLA-DR-beta-1, MHC class II DR beta 1, MHC class II DR beta chain, MHC class II DR beta-chain, MHC class II DR-ALPHA

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Canine, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

17-995-842

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Antigen:
MHC I Free Chain

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
A4

Conjugate:
APC

Gene:
__

Gene Alias:
MHC Free

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

17-998-018

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