200020098

RNASE3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

RNASE3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Mouse

Gene Accession No.

O35290

Gene ID (Entrez)

53876

Immunogen

Recombinant Mouse RNASE3 protein, Phe34-Val150 (Accession #O35290)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

cytotoxic ribonuclease, Ear11, EAR-11, Ear3, ECP, Eosinophil cationic protein, eosinophil cationic protein-like, eosinophil cationic-type ribonuclease 3, Eosinophil secondary granule ribonuclease 11, eosinophil-associated ribonuclease 3, eosinophil-associated, ribonuclease A family, member 3, LOC100361866, mR3, MR-3, murine ribonuclease 3, RAF1, Ribonuclease 3, ribonuclease A family member 3, ribonuclease, RNase A family 3, ribonuclease, RNase A family, 3, RNase 3, RNASE3, RNS3

Gene Symbols

Ear3

Isotype

IgG

Purification Method

Protein A

Gene

Ear3

Related Products

Img

Fischer Scientific

200020098

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020155

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020321

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020239

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020285

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020326

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020264

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020070

Rabbit Polyclonal Antibody...

Description

  • ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family
  • ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system
  • ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils
  • ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities
  • It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death
  • ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020098

Rabbit Polyclonal Antibody...


Antigen:
RNASE3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
O35290

Gene ID (Entrez):
53876

Immunogen:
Recombinant Mouse RNASE3 protein, Phe34-Val150 (Accession #O35290)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
cytotoxic ribonuclease, Ear11, EAR-11, Ear3, ECP, Eosinophil cationic protein, eosinophil cationic protein-like, eosinophil cationic-type ribonuclease 3, Eosinophil secondary granule ribonuclease 11, eosinophil-associated ribonuclease 3, eosinophil-associated, ribonuclease A family, member 3, LOC100361866, mR3, MR-3, murine ribonuclease 3, RAF1, Ribonuclease 3, ribonuclease A family member 3, ribonuclease, RNase A family 3, ribonuclease, RNase A family, 3, RNase 3, RNASE3, RNS3

Gene Symbols:
Ear3

Isotype:
IgG

Purification Method:
Protein A

Gene:
Ear3

Img

Fischer Scientific

200020103

Mouse Monoclonal Antibody...


Antigen:
CRHBP

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P24388

Gene ID (Entrez):
29625

Immunogen:
Recombinant Rat CRHBP protein, Tyr25-Leu322 (Accession #P24388)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
corticotropin releasing factor binding protein, corticotropin releasing hormone binding protein, corticotropin releasing hormone-binding protein, corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein, CRF-binding protein, CRFBP, CRF-BP, Crhbp, CRH-BP

Gene Symbols:
CRHBP

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
CRHBP

Img

Fischer Scientific

200020105

Mouse Monoclonal Antibody...


Antigen:
FAP

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
Q12884

Gene ID (Entrez):
100736572, 2191

Immunogen:
Recombinant Human FAPa protein, Ile523-Asp760 (Accession #Q12884)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
170 kDa melanoma membrane-bound gelatinase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE, Dipeptidyl peptidase FAP, DPPIV, Fap, FAPA, FAPalpha, fibroblast activation protein, fibroblast activation protein alpha, fibroblast activation protein, alpha, gelatine degradation protease FAP, Integral membrane serine protease, post-proline cleaving enzyme, Prolyl endopeptidase FAP, seprase, Serine integral membrane protease, SIMP, Surface-expressed protease

Gene Symbols:
FAP

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
FAP

Img

Fischer Scientific

200020106

Rabbit Polyclonal Antibody...


Antigen:
BACE2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q6IE75, Q9JL18, Q9Y5Z0

Gene ID (Entrez):
25825, 288227, 56175

Immunogen:
Recombinant Rat BACE2 protein, Gly242-Val502 (Accession #Q6IE75)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1110059C24Rik, 56 kDa aspartic-like protease, AEPLC, AI850424, ALP56, ARP1, asp 1, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Bace2, BAE2, be, beta secretase 2, Beta-secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, CDA13, CEAP1, Down region aspartic protease, Down syndrome region aspartic protease, DRAP, memapsin 1, memapsin-1, Membrane-associated aspartic protease 1, theta-secretase, transmembrane aspartic proteinase Asp1, UNQ418/PRO852

Gene Symbols:
BACE2

Isotype:
IgG

Purification Method:
Protein A

Gene:
BACE2