3851545

Arginase I Mouse, Unlabeled, Clone: 19, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Arginase I

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Clone

19

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Drosophila, Mouse, Rat

Immunogen

Human Arginase I aa. 53-207

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Arginase converts arginine into urea plus ornithine, the final step in urea synthesis
  • Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level
  • While type II is present in many tissues, Arginase I is expressed exclusively in liver
  • In cultured macrophages, as well as in vivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPβ in response to lipopolysaccharide
  • This response occurs in a dose and time-dependent manner
  • While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment
  • Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Show Difference

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3851545

Mouse Monoclonal Antibody...


Antigen:
Arginase I

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
19

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Drosophila, Mouse, Rat

Immunogen:
Human Arginase I aa. 53-207

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
GST-π

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
3

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Human GST-π aa. 5-210

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
GST-π

Concentration:
250μg/mL

Classification:
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Host Species:
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Research Discipline:
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Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
3

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Human GST-π aa. 5-210

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Concentration:
250μg/mL

Classification:
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Host Species:
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Research Discipline:
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Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
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Clone:
1

Applications:
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Conjugate:
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Regulatory Status:
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Primary or Secondary:
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