42-009-210T

MilliporeSigma™ anti-PhosphoDetect JAK1 (pTyr1022/1023), Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 42-009-210T-Each-of-1 In Stock ₹ 55,015.08

42-009-210T - Each of 1

₹ 55,015.08

In Stock

Quantity

1

Base Price: ₹ 55,015.08

GST (18%): ₹ 9,902.714

Total Price: ₹ 64,917.794

Antigen

PhosphoDetect™ JAK1 (pTyr1022/1023)

Classification

Polyclonal

Formulation

In Dulbecco's PBS (without Ca2+and Mg2+), 1mg/mL BSA, 50% glycerol, pH 7.3.

Immunogen

a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr1022, superscript_end;and Tyr1023phosphorylation sites of human JAK1 (Janus Kinase 1)

Quantity

10 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse

Isotype

IgG

Applications

Immunoblot

Conjugate

Unconjugated

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Test Specificity

Recognizes the∽130kDa phosphorylated JAK1 in LIF-treated 3T3-L1 cells. Does not cross-react with other JAKs or related kinases.

Content And Storage

≤ -70°C

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Description

  • Specifically detects PhosphoDetect™ JAK1 (pTyr 1022/1023 ) Clone: in Human, Mouse samples, and it is validated for Immuno Blotting In response to cytokines or related factors (interferons, interleukins, etc.), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues, as well as perhaps one or more serine residues
  • Activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activators of transcription) proteins, which dimerize and translocate to the nucleus
  • JAK1 is required for signal transduction through IL-2, IL-4, IL-6, GM-CSF, and interferon receptors.

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Antigen:
PhosphoDetect™ JAK1 (pTyr1022/1023)

Classification:
Polyclonal

Formulation:
In Dulbecco's PBS (without Ca2+and Mg2+), 1mg/mL BSA, 50% glycerol, pH 7.3.

Immunogen:
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr1022, superscript_end;and Tyr1023phosphorylation sites of human JAK1 (Janus Kinase 1)

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Isotype:
IgG

Applications:
Immunoblot

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Test Specificity:
Recognizes the∽130kDa phosphorylated JAK1 in LIF-treated 3T3-L1 cells. Does not cross-react with other JAKs or related kinases.

Content And Storage:
≤ -70°C

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