55-300-910T
MilliporeSigma™ anti-PhosphoDetect c-Raf (pTyr340, Tyr341), Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 55-300-910T-Each-of-1 | In Stock | ₹ 57,678.56 |
55-300-910T - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,678.56
GST (18%): ₹ 10,382.141
Total Price: ₹ 68,060.701
Antigen
PhosphoDetect™ c-Raf (pTyr340, Tyr341)
Classification
Polyclonal
Formulation
In phosphate buffer (without Mg2+and Ca2+), 1mg/mL BSA, 50% glycerol, pH 7.3 (+/- 0.1).
Immunogen
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr340and Tyr341, phosphorylation sites of human c-Raf (Raf-1)
Regulatory Status
RUO
Test Specificity
Recognizes c-Raf phosphorylated at Tyr340and Tyr341in HEK293 cells overexpressing c-Raf.
Content And Storage
−20°C
Isotype
IgG
Applications
Immunocytochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
10 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects PhosphoDetect™ c-Raf (pTyr 340 , Tyr 341 ) Clone: in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry The raf family of proto-oncogenes consists of three members: A-raf-1, B-raf, and c-raf-1 which show the greatest degree of homology in the carboxy-terminal half of the molecule
- In the case of c-raf-1 this region has been shown to have protein (serine/threonine) kinase activity
- C-raf was first identified in an oncogeneic form, v-raf, which is the oncogene of the transforming virus MSV
- The raf-1 gene is the most studied of the three and encodes a protein with an apparent molecular mass of∽74kDa
- Raf is widely expressed and plays an important role in cell proliferation and differentiation
- Raf relays signals related to the activation of growth factor receptor to the activation of MAPK and utlimately to the nucleus
- Activation of raf itself is dependent on tyrosine (341) phosphorylation
- Tyrosine phosphorylation is accomplished by Src tyrosine kinase.
Compare Similar Items
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Antigen: PhosphoDetect™ c-Raf (pTyr340, Tyr341)
Classification: Polyclonal
Formulation: In phosphate buffer (without Mg2+and Ca2+), 1mg/mL BSA, 50% glycerol, pH 7.3 (+/- 0.1).
Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr340and Tyr341, phosphorylation sites of human c-Raf (Raf-1)
Regulatory Status: RUO
Test Specificity: Recognizes c-Raf phosphorylated at Tyr340and Tyr341in HEK293 cells overexpressing c-Raf.
Content And Storage: −20°C
Isotype: IgG
Applications: Immunocytochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
PhosphoDetect™ c-Raf (pTyr340, Tyr341)
Classification:
Polyclonal
Formulation:
In phosphate buffer (without Mg2+and Ca2+), 1mg/mL BSA, 50% glycerol, pH 7.3 (+/- 0.1).
Immunogen:
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr340and Tyr341, phosphorylation sites of human c-Raf (Raf-1)
Regulatory Status:
RUO
Test Specificity:
Recognizes c-Raf phosphorylated at Tyr340and Tyr341in HEK293 cells overexpressing c-Raf.
Content And Storage:
−20°C
Isotype:
IgG
Applications:
Immunocytochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: __
Classification: __
Formulation: A 5 mM (500μg/109μl) solution of Rapamycin in DMSO.
Immunogen: __
Regulatory Status: __
Test Specificity: __
Content And Storage: Hygroscopic, Protect from light
Isotype: __
Applications: __
Conjugate: __
Host Species: __
Quantity: 1 mg
Primary or Secondary: __
Target Species: __
Form: Liquid
Antigen:
__
Classification:
__
Formulation:
A 5 mM (500μg/109μl) solution of Rapamycin in DMSO.
Immunogen:
__
Regulatory Status:
__
Test Specificity:
__
Content And Storage:
Hygroscopic, Protect from light
Isotype:
__
Applications:
__
Conjugate:
__
Host Species:
__
Quantity:
1 mg
Primary or Secondary:
__
Target Species:
__
Form:
Liquid
Antigen: __
Classification: __
Formulation: A 5 mM (500μg/109μl) solution of Rapamycin in DMSO.
Immunogen: __
Regulatory Status: __
Test Specificity: __
Content And Storage: Hygroscopic, Protect from light
Isotype: __
Applications: __
Conjugate: __
Host Species: __
Quantity: 500 μg
Primary or Secondary: __
Target Species: __
Form: Liquid
Antigen:
__
Classification:
__
Formulation:
A 5 mM (500μg/109μl) solution of Rapamycin in DMSO.
Immunogen:
__
Regulatory Status:
__
Test Specificity:
__
Content And Storage:
Hygroscopic, Protect from light
Isotype:
__
Applications:
__
Conjugate:
__
Host Species:
__
Quantity:
500 μg
Primary or Secondary:
__
Target Species:
__
Form:
Liquid
Antigen: __
Classification: __
Formulation: __
Immunogen: __
Regulatory Status: __
Test Specificity: __
Content And Storage: Protect from light
Isotype: __
Applications: __
Conjugate: __
Host Species: __
Quantity: 10 mg
Primary or Secondary: __
Target Species: __
Form: Solid
Antigen:
__
Classification:
__
Formulation:
__
Immunogen:
__
Regulatory Status:
__
Test Specificity:
__
Content And Storage:
Protect from light
Isotype:
__
Applications:
__
Conjugate:
__
Host Species:
__
Quantity:
10 mg
Primary or Secondary:
__
Target Species:
__
Form:
Solid