4358228

CD86 Mouse anti-Human, Brilliant Violet 421, Clone: 2331 (FUN-1), BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD86

Applications

Flow Cytometry

Conjugate

Brilliant Violet 421

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

Clone

2331 (FUN-1)

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human HBL-1 Cell Line

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 2331 (FUN-1) monoclonal antibody specifically recognizes a 75 kDa transmembrane cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes, dendritic cells and activated B cells
  • Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Cat
  • No
  • 555663) antibodies specifically recognize the same molecule, they react with different epitopes
  • CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response
  • The 2331 (FUN-1) antibody blocks the costimulatory activity of CD86 when tested in functional studies.The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen
  • With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter)
  • Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
  • Host Species: Mouse Clone: 2331 (FUN-1) Isotype: IgG1, κ Species Reactivity: Human Flow Cytometry

Compare Similar Items

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Fischer Scientific

4358228

Mouse Monoclonal Antibody...


Antigen:
CD86

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

Clone:
2331 (FUN-1)

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human HBL-1 Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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4358229

Mouse Monoclonal Antibody...


Antigen:
CD8

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32

Clone:
RPA-T8

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Immunogen:
Human CD8a

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD19

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B4; B-lymphocyte antigen CD19; Leu-12

Clone:
HIB19

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD25

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55

Clone:
M-A251

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.