44-436-G

BID p15 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 44-436-G-Each-of-1 In Stock ₹ 36,790.80

44-436-G - Each of 1

₹ 36,790.80

In Stock

Quantity

1

Base Price: ₹ 36,790.80

GST (18%): ₹ 6,622.344

Total Price: ₹ 43,413.144

Antigen

BID p15

Classification

Polyclonal

Formulation

Dulbecco's PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3

Gene Accession No.

P55957, P70444

Gene Symbols

BID

Immunogen

The antiserum was produced against a chemically synthesized peptide derived from the 15 kDa caspase-8 cleavage product of mouse BID.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Gene

BID

Gene Alias

2700049M22Rik; AI875481; apoptic d; apoptic death agonist; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; BID; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12122, 637

Content And Storage

-20°C

Form

Liquid

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Description

  • BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2
  • Bid is a member of the BCL-2 family of cell death regulators
  • BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release
  • BID is also a pro-apoptotic member of the Bcl 2 family
  • BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand
  • Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis
  • BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.

Compare Similar Items

Show Difference

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Invitrogen

44-436-G

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Antigen:
BID p15

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P55957, P70444

Gene Symbols:
BID

Immunogen:
The antiserum was produced against a chemically synthesized peptide derived from the 15 kDa caspase-8 cleavage product of mouse BID.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
BID

Gene Alias:
2700049M22Rik; AI875481; apoptic d; apoptic death agonist; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; BID; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12122, 637

Content And Storage:
-20°C

Form:
Liquid

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Applied Biosystems™

44-437-64

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Antigen:
__

Classification:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
Sequence Analysis Software

Isotype:
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Applications:
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Conjugate:
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Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
2 to 8°C

Form:
__

Img

Applied Biosystems™

44-437-74

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Antigen:
__

Classification:
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Formulation:
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Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
1 x 96-well plate

Primary or Secondary:
__

Target Species:
__

Product Type:
Normalization Kit

Isotype:
__

Applications:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store at –20°C ± 5°C.

Form:
__

Img

Applied Biosystems™

44-437-89

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Antigen:
__

Classification:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
100 reactions

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Includes buffers, magnetic beads and enzymes for DNA extraction for Mycoplasma DNA extraction

Form:
__