4552781

MMP-2 (72kDa Collagenase IV) Ab-1 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in experiments with the Epredia™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

MMP-2 (72kDa Collagenase IV) Ab-1

Applications

Western Blot

Form

Concentrated

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Isotype

IgG1

Clone

CA-4001 or CA719E3C

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Proteases And Inhibitors

Immunogen

N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Primary or Secondary

Primary

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Description

  • MMPs are proteolytic enzymes capable of degrading connective tissue components
  • They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs)
  • MMPs and TIMPs play a significant role in regulating angiogenesis
  • MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form.of 62kDa
  • Host Species: Mouse Clone: CA-4001 or CA719E3C Isotype: IgG1 Species Reactivity: Human, Mouse and Rat
  • Others not known
  • Epitope: N-terminal (APSPIIKFPGD-VAPKTDK) Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV Molecular Weight: 72kDa (proform) Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells Cellular Localization: Cytoplasmic Recommended for: Western Blotting Immunoprecipitation (Not suitable) Inhibition of MMP-2 Activity Note: USA: RUO; Int'l: RUO

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Antigen:
MMP-2 (72kDa Collagenase IV) Ab-1

Applications:
Western Blot

Form:
Concentrated

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Clone:
CA-4001 or CA719E3C

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Proteases And Inhibitors

Immunogen:
N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Primary or Secondary:
Primary

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4552782

Epredia™ MMP-2 (72kDa Collagenase I...


Antigen:
MMP-2 (72kDa Collagenase IV) Ab-2

Applications:
Immunofluorescence, Immunoprecipitation, Western Blot

Form:
Concentrated

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Clone:
VB3

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Proteases And Inhibitors

Immunogen:
Human native 72kDa MMP-2

Primary or Secondary:
Primary

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4552784

Epredia™ MMP-3 (Stromelysin-1) Ab-1...


Antigen:
MMP-3 (Stromelysin-1) Ab-1

Applications:
Immunofluorescence, Western Blot

Form:
Concentrated

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Clone:
SL-1 ID3

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Proteases And Inhibitors

Immunogen:
APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)

Primary or Secondary:
Primary

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