4552782
MMP-2 (72kDa Collagenase IV) Ab-2 Mouse Monoclonal Antibody, Epredia™
Epredia™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Fischer Scientific
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Antigen
MMP-2 (72kDa Collagenase IV) Ab-2
Applications
Immunofluorescence, Immunoprecipitation, Western Blot
Form
Concentrated
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Clone
VB3
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Proteases And Inhibitors
Immunogen
Human native 72kDa MMP-2
Primary or Secondary
Primary
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Description
- MMPs are proteolytic enzymes capable of degrading connective tissue components
- They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs)
- MMPs and TIMPs play a significant role in regulating angiogenesis
- MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids
- Host Species: Mouse Clone: VB3 Isotype: IgG1/κ Species Reactivity: Human
- Others not known
- Epitope: Not determined Immunogen: Human native 72kDa MMP-2 Molecular Weight: 72kDa (proform) and ∽66kDa (active form) Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Not Suitable) Western Blotting Immunofluorescence Immunoprecipitation (Native verified) Note: USA: RUO; Int'l: RUO
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Antigen: MMP-2 (72kDa Collagenase IV) Ab-2
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Form: Concentrated
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Clone: VB3
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Proteases And Inhibitors
Immunogen: Human native 72kDa MMP-2
Primary or Secondary: Primary
Antigen:
MMP-2 (72kDa Collagenase IV) Ab-2
Applications:
Immunofluorescence, Immunoprecipitation, Western Blot
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Clone:
VB3
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Proteases And Inhibitors
Immunogen:
Human native 72kDa MMP-2
Primary or Secondary:
Primary
Antigen: MMP-3 (Stromelysin-1) Ab-1
Applications: Immunofluorescence, Western Blot
Form: Concentrated
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Clone: SL-1 ID3
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Proteases And Inhibitors
Immunogen: APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)
Primary or Secondary: Primary
Antigen:
MMP-3 (Stromelysin-1) Ab-1
Applications:
Immunofluorescence, Western Blot
Form:
Concentrated
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Clone:
SL-1 ID3
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Proteases And Inhibitors
Immunogen:
APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)
Primary or Secondary:
Primary
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