50-112-2085

CD98hc Monoclonal Antibody (5E5), FITC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 50-112-2085-Each In Stock ₹ 20,418.89

50-112-2085 - Each

₹ 20,418.89

In Stock

Quantity

1

Base Price: ₹ 20,418.89

GST (18%): ₹ 3,675.40

Total Price: ₹ 24,094.29

Antigen

CD98hc

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P08195

Gene Symbols

SLC3A2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6520

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

5E5

Conjugate

FITC

Gene

SLC3A2

Gene Alias

4F2; 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; 4T2HC; AI314110; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; Cd98; CD98 antigen; CD98 heavy chain; CD98HC; Ly10; Ly-10; Ly-m10; Lymphocyte activation antigen 4F2 large subunit; MDU1; Mgp-2hc; monoclonal antibody 44D7; NACAE; RGD:3073}; SLC3A2; slc3a2 {ECO:0000312; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3 member 2; solute carrier family 3, member 2; type II transmembrane protein

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The monoclonal antibody 5E5 recognizes human CD98hc protein also called CD98 heavy chain, FRP-1 (fusion regulatory protein-1 ) or 4F2
  • CD98 is a disulfide-linked complex composed of a heavy chain (a Type II membrane protein) and a light chain of which there are more than six different chains (LAT1, LAT2, y+LAT1, y+LAT2, Asc-1, xCT)
  • CD98 can associate directly or indirectly with beta 1 integrins, EpCAM and CD147 (EMMPRIN)
  • The function of CD98 is thought to involve amino acid transport, cell fusion concomitantly with increased plasma membrane expression and integrin mediated adhesion
  • Expression of CD98 is broad including non-hematopoietic cells
  • In peripheral blood cells, monocytes expression is high while lymphocytes have intermediate levels and granulocytes express very little
  • Applications Reported: This 5E5 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 5E5 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs)
  • CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand
  • Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation
  • It is implicated in regulation of cellular differentiation, growth and apoptosis.

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Show Difference

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Invitrogen

50-112-2085

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Antigen:
CD98hc

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P08195

Gene Symbols:
SLC3A2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6520

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
5E5

Conjugate:
FITC

Gene:
SLC3A2

Gene Alias:
4F2; 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; 4T2HC; AI314110; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; Cd98; CD98 antigen; CD98 heavy chain; CD98HC; Ly10; Ly-10; Ly-m10; Lymphocyte activation antigen 4F2 large subunit; MDU1; Mgp-2hc; monoclonal antibody 44D7; NACAE; RGD:3073}; SLC3A2; slc3a2 {ECO:0000312; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3 member 2; solute carrier family 3, member 2; type II transmembrane protein

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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50-112-2091

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Antigen:
CD117 (c-Kit)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P10721

Gene Symbols:
KIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3815

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
104D2

Conjugate:
FITC

Gene:
KIT

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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50-112-2093

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Antigen:
CD122

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P14784

Gene Symbols:
Il2rb

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3560

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
TU27

Conjugate:
FITC

Gene:
Il2rb

Gene Alias:
CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; IL2RB; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; p70-75; p75

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
CD172a (SIRP alpha)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P78324

Gene Symbols:
SIRPA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140885

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
15-414

Conjugate:
FITC

Gene:
SIRPA

Gene Alias:
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ