50-112-4422
TOX Monoclonal Antibody (TXRX10), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4422-Each-of-1 | In Stock | ₹ 16,256.40 |
50-112-4422 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,256.40
GST (18%): ₹ 2,926.152
Total Price: ₹ 19,182.552
Antigen
TOX
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O94900, Q66JW3
Gene Symbols
TOX
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
252838, 9760
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
TXRX10
Conjugate
eFluor 660
Gene
TOX
Gene Alias
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This TXRX10 monoclonal antibody reacts with human and mouse TOX, which is also known as Thymocyte selection-associated HMG box protein
- This DNA-binding nuclear factor is expressed in thymocytes, T lymphocytes, NK cells, and lymphoid tissue-inducer (LTi) cells
- TOX expression in thymocytes is upregulated during beta-selection and positive selection
- Studies using Tox knockout mice have demonstrated a critical role for TOX in CD4+ T cell development as a regulator of the CD4loCD8lo to CD4+CD8lo transition
- Moreover, TOX has been shown to be involved in the development of NK and LTi cells
- While its regulation remains unclear, TOX expression has been shown to be induced by calcineurin-mediated TCR signaling in thymocytes during positive selection
- Applications Reported: This TXRX10 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This TXRX10 antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcriptin Factor Buffer Set (cat 00-5523) and protocol
- Refer to Best Protocols- (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins)
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development
- It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes
- TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent
- TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Compare Similar Items
Show Difference
Antigen: TOX
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O94900, Q66JW3
Gene Symbols: TOX
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 252838, 9760
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TXRX10
Conjugate: eFluor 660
Gene: TOX
Gene Alias: 1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TOX
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O94900, Q66JW3
Gene Symbols:
TOX
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
252838, 9760
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TXRX10
Conjugate:
eFluor 660
Gene:
TOX
Gene Alias:
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: TOX
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O94900, Q66JW3
Gene Symbols: TOX
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 252838, 9760
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TXRX10
Conjugate: eFluor 660
Gene: TOX
Gene Alias: 1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TOX
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O94900, Q66JW3
Gene Symbols:
TOX
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
252838, 9760
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TXRX10
Conjugate:
eFluor 660
Gene:
TOX
Gene Alias:
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Myosin 4
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene Symbols: MYH4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: MF20
Conjugate: eFluor 660
Gene: MYH4
Gene Alias: 2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Myosin 4
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene Symbols:
MYH4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone:
MF20
Conjugate:
eFluor 660
Gene:
MYH4
Gene Alias:
2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: __
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Product Type: Phalloidin
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Product Type:
Phalloidin
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