50-112-4423
TOX Monoclonal Antibody (TXRX10), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4423-Each-of-1 | In Stock | ₹ 40,127.64 |
50-112-4423 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,127.64
GST (18%): ₹ 7,222.975
Total Price: ₹ 47,350.615
Antigen
TOX
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O94900, Q66JW3
Gene Symbols
TOX
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
252838, 9760
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
TXRX10
Conjugate
eFluor 660
Gene
TOX
Gene Alias
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This TXRX10 monoclonal antibody reacts with human and mouse TOX, which is also known as Thymocyte selection-associated HMG box protein
- This DNA-binding nuclear factor is expressed in thymocytes, T lymphocytes, NK cells, and lymphoid tissue-inducer (LTi) cells
- TOX expression in thymocytes is upregulated during beta-selection and positive selection
- Studies using Tox knockout mice have demonstrated a critical role for TOX in CD4+ T cell development as a regulator of the CD4loCD8lo to CD4+CD8lo transition
- Moreover, TOX has been shown to be involved in the development of NK and LTi cells
- While its regulation remains unclear, TOX expression has been shown to be induced by calcineurin-mediated TCR signaling in thymocytes during positive selection
- Applications Reported: This TXRX10 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This TXRX10 antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcriptin Factor Buffer Set (cat 00-5523) and protocol
- Refer to Best Protocols- (refer to Protocol B: One-step protocol for intracellular (nuclear) proteins)
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development
- It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes
- TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent
- TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Compare Similar Items
Show Difference
Antigen: TOX
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O94900, Q66JW3
Gene Symbols: TOX
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 252838, 9760
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TXRX10
Conjugate: eFluor 660
Gene: TOX
Gene Alias: 1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TOX
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O94900, Q66JW3
Gene Symbols:
TOX
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
252838, 9760
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TXRX10
Conjugate:
eFluor 660
Gene:
TOX
Gene Alias:
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Myosin 4
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene Symbols: MYH4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: MF20
Conjugate: eFluor 660
Gene: MYH4
Gene Alias: 2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Myosin 4
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene Symbols:
MYH4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone:
MF20
Conjugate:
eFluor 660
Gene:
MYH4
Gene Alias:
2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
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Gene: __
Gene Alias: __
Host Species: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: Phalloidin
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
Phalloidin
Isotype:
__
Antigen: IL-13
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P20109
Gene Symbols: Il13
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16163
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio13A
Conjugate: eFluor 660
Gene: Il13
Gene Alias: ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IL-13
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P20109
Gene Symbols:
Il13
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16163
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio13A
Conjugate:
eFluor 660
Gene:
Il13
Gene Alias:
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ