50-199-0580
TRPC6 Monoclonal Antibody (3F2.H10.F2), Rockland™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-0580-Each-of-1 | In Stock | ₹ 14,374.08 |
50-199-0580 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,374.08
GST (18%): ₹ 2,587.334
Total Price: ₹ 16,961.414
Antigen
TRPC6
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
Q9Y210
Gene Symbols
Trpc6
Immunogen
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein.
Regulatory Status
RUO
Gene ID (Entrez)
451503, 7225
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
3F2.H10.F2
Conjugate
Unconjugated
Gene
Trpc6
Gene Alias
AV025995; Calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; Trp6; TRP-6; trp6A; TRPC6; Trrp6
Host Species
Mouse
Quantity
25 μL
Primary or Secondary
Primary
Target Species
Chimpanzee, Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is specific for human TRPC6 protein
- A BLAST analysis was used to suggest cross-reactivity with TRPC6 from chimpanzee based on 100% homology with the immunizing sequence
- Cross-reactivity with TRPC6 from other sources has not been determined
- Trpc6 forms a receptor-activated calcium channel in the cell membrane
- The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
- Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
- Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
- Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the 'canonical TRP' (TRPC) family
- The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
- Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
- When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
- Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
- There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
- Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.
Compare Similar Items
Show Difference
Antigen: TRPC6
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q9Y210
Gene Symbols: Trpc6
Immunogen: This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein.
Regulatory Status: RUO
Gene ID (Entrez): 451503, 7225
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 3F2.H10.F2
Conjugate: Unconjugated
Gene: Trpc6
Gene Alias: AV025995; Calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; Trp6; TRP-6; trp6A; TRPC6; Trrp6
Host Species: Mouse
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Chimpanzee, Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
TRPC6
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q9Y210
Gene Symbols:
Trpc6
Immunogen:
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein.
Regulatory Status:
RUO
Gene ID (Entrez):
451503, 7225
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
3F2.H10.F2
Conjugate:
Unconjugated
Gene:
Trpc6
Gene Alias:
AV025995; Calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; Trp6; TRP-6; trp6A; TRPC6; Trrp6
Host Species:
Mouse
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Chimpanzee, Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: 6X His Tag
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Immunogen: 6X HIS antibody was produced in mice by repeated immunizations with 6X His epitope tag peptide H-H-H-H-H-H conjugated to KLH using maleimide.
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 33D10.D2.G8
Conjugate: Unconjugated
Gene: __
Gene Alias: 6His tag; 6X His; His Tag; Histidine Tag
Host Species: Mouse
Quantity: 1 mg
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
6X His Tag
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
6X HIS antibody was produced in mice by repeated immunizations with 6X His epitope tag peptide H-H-H-H-H-H conjugated to KLH using maleimide.
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
33D10.D2.G8
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
6His tag; 6X His; His Tag; Histidine Tag
Host Species:
Mouse
Quantity:
1 mg
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: IDO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P14902, P28776
Gene Symbols: Ido1
Immunogen: Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Regulatory Status: RUO
Gene ID (Entrez): 15930, 3620
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 10.1
Conjugate: Unconjugated
Gene: Ido1
Gene Alias: EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG3
Antigen:
IDO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P14902, P28776
Gene Symbols:
Ido1
Immunogen:
Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Regulatory Status:
RUO
Gene ID (Entrez):
15930, 3620
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
10.1
Conjugate:
Unconjugated
Gene:
Ido1
Gene Alias:
EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG3
Antigen: IDO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P14902, P28776
Gene Symbols: Ido1
Immunogen: Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Regulatory Status: RUO
Gene ID (Entrez): 15930, 3620
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 10.1
Conjugate: Unconjugated
Gene: Ido1
Gene Alias: EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Host Species: Mouse
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG3
Antigen:
IDO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P14902, P28776
Gene Symbols:
Ido1
Immunogen:
Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Regulatory Status:
RUO
Gene ID (Entrez):
15930, 3620
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
10.1
Conjugate:
Unconjugated
Gene:
Ido1
Gene Alias:
EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Host Species:
Mouse
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG3