7190621

NOTCH 1 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

NOTCH 1

Applications

Dot Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

P46531, Q01705, Q07008

Gene ID (Entrez)

18128, 25496, 4851

Immunogen

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 1 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Notch1

Concentration

90 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Alias

9930111A19Rik; AOS5; AOVD1; BOS_12152; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; Neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; Notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; NOTCH1; p300; RP23-306D20.12; RP23-306D20.12-001; TAN1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1

Gene Symbols

Notch1

Primary or Secondary

Primary

Product Type

Antibody

Related Products

Img

Fischer Scientific

50-194-3772

--

Img

Fischer Scientific

7188832

Rat Monoclonal Antibody...

Img

Fischer Scientific

7190883

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7190726

Mouse Monoclonal Antibody...

Img

Fischer Scientific

50-199-0580

--

Img

Fischer Scientific

50-199-0579

--

Img

Fischer Scientific

7191040

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7191131

Rabbit Polyclonal Antibody...

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antiserum is directed against human NOTCH 1
  • Based on the immunogen sequence, we expect this antibody to react as well with mouse and rat NOTCH 1 (100% sequence homology)
  • This antibody reacts with mouse Notch constructs present in lysates of HEK 293 cells
  • Only the cleaved intracellular (activated) form (NICD) is detected
  • No reactivity is detected against mouse N2, N3 or N4
  • The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form
  • The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region
  • Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures
  • The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1
  • Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).

Compare Similar Items

Show Difference

Img

Fischer Scientific

7190621

Rabbit Polyclonal Antibody...


Antigen:
NOTCH 1

Applications:
Dot Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P46531, Q01705, Q07008

Gene ID (Entrez):
18128, 25496, 4851

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 1 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Notch1

Concentration:
90 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Alias:
9930111A19Rik; AOS5; AOVD1; BOS_12152; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; Neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; Notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; NOTCH1; p300; RP23-306D20.12; RP23-306D20.12-001; TAN1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1

Gene Symbols:
Notch1

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190627

Rabbit Polyclonal Antibody...


Antigen:
ATG13

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O75143

Gene ID (Entrez):
9776

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
ATG13

Concentration:
1.13 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
1110053A20Rik; ATG13; ATG13 autophagy related 13 homolog; autophagy related 13; Autophagy-related protein 13; D2Ertd391e; FLJ20698; Harbi1; Harbi1l; harbinger transposase derived 1; Kiaa0652; OTTHUMP00000233321; OTTHUMP00000233322; OTTHUMP00000233323; OTTHUMP00000233324; OTTHUMP00000233325; OTTHUMP00000233326; PARATARG8; RGD1310685

Gene Symbols:
ATG13

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190629

Rabbit Polyclonal Antibody...


Antigen:
Urease

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Plant

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Urease [Jack Bean]

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
Urea Amidohydrolase

Gene Symbols:
__

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190634

Rabbit Polyclonal Antibody...


Antigen:
SIRT1

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q96EB6

Gene ID (Entrez):
23411

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
SIRT1

Concentration:
1.07 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; Sir2; Sir2a; SIR2alpha; Sir2l1; sir2-like 1; SIR2-like protein 1; SIRT1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1

Gene Symbols:
SIRT1

Primary or Secondary:
Primary

Product Type:
Antibody