51-537-542
IRF7 Monoclonal Antibody (RDP4ND4), Alexa Fluor™ 647, eBioscience™, Invitrogen™
Manufacturer: eBioscience
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 51-537-542-Each-of-1 | In Stock | ₹ 36,504.17 |
51-537-542 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,504.17
GST (18%): ₹ 6,570.751
Total Price: ₹ 43,074.921
Antigen
IRF7
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q92985
Gene Symbols
IRF7
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3665
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
RDP4ND4
Conjugate
Alexa Fluor 647
Gene
IRF7
Gene Alias
IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; Irf7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H
Host Species
Rat
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The monoclonal antibody RDP4ND4 recognizes human interferon regulatory factor 7 (IRF7), a 54 kDa member of the interferon regulatory transcription factor family
- It is essential for the antiviral innate immune response and the activation of type I IFN genes
- IRF7 is constitutively expressed in the cytoplasm of plasmacytoid dendritic cells, B cells and monocytes, but it is strongly induced in response to virus infection and interferon stimulation
- IRF7 can activate IFN-beta and IFN-alpha genes via the virus-activated, MyD88-independent pathway, or the TLR-activated, MyD88-dependent pathway
- Virus exposure induces IRF7, through toll-like receptors TLR7, TLR8, and TLR9, to promote IFN gene expression and disrupt infection
- IRF7 exists in an inactive form until phosphorylated and its phosphorylation leads to dimerization and nuclear translocation of IRF7 where it aids in activating target genes
- The IRF7 gene is upregulated by interferon stimulation through the Jak-STAT pathway in a positive feedback loop
- Applications Reported: This RDP4ND4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This RDP4ND4 antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells using the Foxp3/Transcription Factor Staining Buffer Set (Product No
- 00-5523) and protocol
- Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms
- During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes
- IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes
- IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling
- There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
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Antigen: IRF7
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q92985
Gene Symbols: IRF7
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3665
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: RDP4ND4
Conjugate: Alexa Fluor 647
Gene: IRF7
Gene Alias: IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; Irf7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H
Host Species: Rat
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
IRF7
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q92985
Gene Symbols:
IRF7
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3665
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RDP4ND4
Conjugate:
Alexa Fluor 647
Gene:
IRF7
Gene Alias:
IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; Irf7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H
Host Species:
Rat
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: LIN7C
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: O88952, Q792I0, Q9NUP9
Gene Symbols: LIN7C
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22343, 485424, 55327, 60442
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: LIN7C
Gene Alias: 9130007B12Rik; AI303698; AU019331; AW125731; D2Ertd520e; EGK_06400; fb75b09; FLJ11215; lin 7 homolog c; lin-7 homolog C; lin-7 homolog C (C. elegans); lin-7 homolog C, crumbs cell polarity complex component; LIN-7 protein 3; Lin7c; LIN-7C; lin-7-C; lin7c protein; MALS3; MALS-3; Mammalian lin-seven protein 3; mLin7C; neuroepithelial polarity protein; protein lin-7 homolog C; Protein lin-7-like protein C; Unknown (protein for MGC:140723); Veli3; veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; vertebrate lin-7 homolog 3; wu:fb75b09; zgc:101881
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LIN7C
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
O88952, Q792I0, Q9NUP9
Gene Symbols:
LIN7C
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22343, 485424, 55327, 60442
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
LIN7C
Gene Alias:
9130007B12Rik; AI303698; AU019331; AW125731; D2Ertd520e; EGK_06400; fb75b09; FLJ11215; lin 7 homolog c; lin-7 homolog C; lin-7 homolog C (C. elegans); lin-7 homolog C, crumbs cell polarity complex component; LIN-7 protein 3; Lin7c; LIN-7C; lin-7-C; lin7c protein; MALS3; MALS-3; Mammalian lin-seven protein 3; mLin7C; neuroepithelial polarity protein; protein lin-7 homolog C; Protein lin-7-like protein C; Unknown (protein for MGC:140723); Veli3; veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; vertebrate lin-7 homolog 3; wu:fb75b09; zgc:101881
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: KLRG1
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O88713
Gene Symbols: Klrg1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50928
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 2F1
Conjugate: Alexa Fluor 647
Gene: Klrg1
Gene Alias: 2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor
Host Species: Syrian Hamster
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
KLRG1
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O88713
Gene Symbols:
Klrg1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50928
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
2F1
Conjugate:
Alexa Fluor 647
Gene:
Klrg1
Gene Alias:
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor
Host Species:
Syrian Hamster
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Tau
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P10636
Gene Symbols: MAPT
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4137
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: HT7
Conjugate: Alexa Fluor 647
Gene: MAPT
Gene Alias: AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Tau
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P10636
Gene Symbols:
MAPT
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4137
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
HT7
Conjugate:
Alexa Fluor 647
Gene:
MAPT
Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ