53-193-942
CD193 (CCR3) Monoclonal Antibody (eBio5E8-G9-B4 (5E8-G9-B4)), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-193-942-Each-of-1 | In Stock | ₹ 31,229.40 |
53-193-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,229.40
GST (18%): ₹ 5,621.292
Total Price: ₹ 36,850.692
Antigen
CD193 (CCR3)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P51677
Gene Symbols
CCR3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1232
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio5E8-G9-B4 (5E8-G9-B4)
Conjugate
Alexa Fluor 488
Gene
CCR3
Gene Alias
b-chemokine receptor, CC chemokine receptor 3, C-C chemokine receptor type 3, C-C CKR-3, C-C motif chemokine receptor 3, CC-CKR3, CC-CKR-3, Ccr3, CCR-3, CD193, chemokine (C-C motif) receptor 3, chemokine (C-C) receptor 1,-like 2, chemokine (C-C) receptor 3, CKR3, Cmkbr1l2, CMKBR3, eosinophil CC chemokine receptor 3, eosinophil eotaxin receptor, Macrophage inflammatory protein 1-alpha receptor-like 2, MGC102841, MIP-1 alpha RL2, MIP-1 alphaRL2, probable C-C chemokine receptor type 3
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The eBio5E8-G9-B4 monoclonal antibody reacts with human CD193 (CCR3, CKR3)
- CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4
- CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function
- In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells
- CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma
- CD193 can also serve as a receptor for HIV-1 cell entry
- Applications Reported: This eBio5E8-G9-B4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBio5E8-G9-B4 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta
- CCR3 trasnduces a signal by increasing the intracellular calcium ions level
- It also serves as an alternative co-receptor with CD4 for HIV-1 infection
- Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection
- Chemokines activate leukocytes by binding to G protein coupled receptors
- The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.
Compare Similar Items
Show Difference
Antigen: CD193 (CCR3)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P51677
Gene Symbols: CCR3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1232
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio5E8-G9-B4 (5E8-G9-B4)
Conjugate: Alexa Fluor 488
Gene: CCR3
Gene Alias: b-chemokine receptor, CC chemokine receptor 3, C-C chemokine receptor type 3, C-C CKR-3, C-C motif chemokine receptor 3, CC-CKR3, CC-CKR-3, Ccr3, CCR-3, CD193, chemokine (C-C motif) receptor 3, chemokine (C-C) receptor 1,-like 2, chemokine (C-C) receptor 3, CKR3, Cmkbr1l2, CMKBR3, eosinophil CC chemokine receptor 3, eosinophil eotaxin receptor, Macrophage inflammatory protein 1-alpha receptor-like 2, MGC102841, MIP-1 alpha RL2, MIP-1 alphaRL2, probable C-C chemokine receptor type 3
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD193 (CCR3)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P51677
Gene Symbols:
CCR3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1232
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio5E8-G9-B4 (5E8-G9-B4)
Conjugate:
Alexa Fluor 488
Gene:
CCR3
Gene Alias:
b-chemokine receptor, CC chemokine receptor 3, C-C chemokine receptor type 3, C-C CKR-3, C-C motif chemokine receptor 3, CC-CKR3, CC-CKR-3, Ccr3, CCR-3, CD193, chemokine (C-C motif) receptor 3, chemokine (C-C) receptor 1,-like 2, chemokine (C-C) receptor 3, CKR3, Cmkbr1l2, CMKBR3, eosinophil CC chemokine receptor 3, eosinophil eotaxin receptor, Macrophage inflammatory protein 1-alpha receptor-like 2, MGC102841, MIP-1 alpha RL2, MIP-1 alphaRL2, probable C-C chemokine receptor type 3
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD194 (CCR4)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P51679
Gene Symbols: Ccr4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1233
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: D8SEE
Conjugate: Alexa Fluor 488
Gene: Ccr4
Gene Alias: C-C chemokine receptor 4; C-C chemokine receptor type 4; C-C CKR-4; C-C motif chemokine receptor 4; CC-CKR-4; Ccr4; CCR-4; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; CHEMR1; ChemR13; CKR4; Cmkbr4; fusin; HGCN:14099; K5-5; LESTR; leukocyte-expressed seven-transmembrane-domain receptor; MGC88293; Sdf1r
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD194 (CCR4)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P51679
Gene Symbols:
Ccr4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1233
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
D8SEE
Conjugate:
Alexa Fluor 488
Gene:
Ccr4
Gene Alias:
C-C chemokine receptor 4; C-C chemokine receptor type 4; C-C CKR-4; C-C motif chemokine receptor 4; CC-CKR-4; Ccr4; CCR-4; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; CHEMR1; ChemR13; CKR4; Cmkbr4; fusin; HGCN:14099; K5-5; LESTR; leukocyte-expressed seven-transmembrane-domain receptor; MGC88293; Sdf1r
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 50 mg
Primary or Secondary: __
Target Species: __
Product Type: ACT 462206
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
50 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
ACT 462206
Isotype:
__
Antigen: CD195 (CCR5)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P51681
Gene Symbols: CCR5
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1234
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: NP-6G4
Conjugate: Alexa Fluor 488
Gene: CCR5
Gene Alias: AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD195 (CCR5)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P51681
Gene Symbols:
CCR5
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1234
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
NP-6G4
Conjugate:
Alexa Fluor 488
Gene:
CCR5
Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ