56-193-942

CD193 (CCR3) Monoclonal Antibody (eBio5E8-G9-B4 (5E8-G9-B4)), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 56-193-942-Each-of-1 In Stock ₹ 31,229.40

56-193-942 - Each of 1

₹ 31,229.40

In Stock

Quantity

1

Base Price: ₹ 31,229.40

GST (18%): ₹ 5,621.292

Total Price: ₹ 36,850.692

Antigen

CD193 (CCR3)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P51677

Gene Symbols

CCR3

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1232

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBio5E8-G9-B4 (5E8-G9-B4)

Conjugate

Alexa Fluor 700

Gene

CCR3

Gene Alias

b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; Ccr3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; probable C-C chemokine receptor type 3

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • The eBio5E8-G9-B4 MAb reacts with human CD193 (CCR3, CKR3)
  • CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4
  • CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function
  • In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells
  • CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma
  • CD193 can also serve as a receptor for HIV-1 cell entry
  • CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta
  • CCR3 trasnduces a signal by increasing the intracellular calcium ions level
  • It also serves as an alternative co-receptor with CD4 for HIV-1 infection
  • Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection
  • Chemokines activate leukocytes by binding to G protein coupled receptors
  • The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.

Compare Similar Items

Show Difference

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Invitrogen

56-193-942

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Antigen:
CD193 (CCR3)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P51677

Gene Symbols:
CCR3

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1232

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBio5E8-G9-B4 (5E8-G9-B4)

Conjugate:
Alexa Fluor 700

Gene:
CCR3

Gene Alias:
b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; Ccr3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; probable C-C chemokine receptor type 3

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

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Invitrogen

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Antigen:
CD206 (MMR)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q61830

Gene Symbols:
Mrc1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17533

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MR6F3

Conjugate:
Alexa Fluor 700

Gene:
Mrc1

Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Invitrogen

56-206-942

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Antigen:
CD206 (MMR)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P22897

Gene Symbols:
Mrc1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4360

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
19.2

Conjugate:
Alexa Fluor 700

Gene:
Mrc1

Gene Alias:
AW259686, bA541I19.1, CD206, CELE_Y39A3CR.4, CLEC13D, CLEC13DL, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, ddp-1, hMR, Human mannose receptor, macrophage mannose receptor 1, Macrophage mannose receptor 1-like protein 1, mannose receptor, C type 1, mannose receptor, C type 1-like 1, Mitochondrial import inner membrane translocase subunit Tim8, MMR, MR, MRC1, MRC1L1, tim-8, Y39A3CR.4

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

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Fischer Scientific

56-221-0

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Antigen:
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Classification:
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Concentration:
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Formulation:
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Gene Accession No.:
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Purification Method:
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Clone:
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Gene:
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Quantity:
10 mg

Primary or Secondary:
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Isotype:
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