53-195-642
CD195 (CCR5) Monoclonal Antibody (NP-6G4), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 53-195-642-Each | In Stock | ₹ 27,520.37 |
53-195-642 - Each
In Stock
Quantity
1
Base Price: ₹ 27,520.37
GST (18%): ₹ 4,953.667
Total Price: ₹ 32,474.037
Antigen
CD195 (CCR5)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P51681
Gene Symbols
CCR5
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1234
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
NP-6G4
Conjugate
Alexa Fluor 488
Gene
CCR5
Gene Alias
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The NP-6G4 monoclonal antibody reacts with human CD195 (CCR5), an approximately 45 kDa member of the G protein-coupled receptor (GPCR) superfamily that binds chemokines including MIP-1a, MIP-1b and RANTES
- Human CCR5 is expressed on resting T cells with a memory/effector phenotype, monocytes, macrophages and immature dendritic cells
- CCR5 functions as a receptor to direct the chemotaxis of lymphocytes, and is the primary co-receptor for macrophage-tropic Human Immunodeficiency Virus Type 1 (HIV-1), which binds CCR5 through gp120
- Applications Reported: This NP-6G4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This NP-6G4 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- For optimal performance, it is recommended that staining with NP-6G4 be done at 37°C for 1 hour in Flow Cytometry Staining Buffer (Product # 00-4222-26)
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells
- Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors
- Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells
- CCR5 is required for the infection by HIV-1, HIV-2, and SIV
- The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1
- CCR5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells
- The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites
- CCR5 messenger RNA is expressed in lymphoid organs and monocytes.
Compare Similar Items
Show Difference
Antigen: CD195 (CCR5)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P51681
Gene Symbols: CCR5
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1234
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: NP-6G4
Conjugate: Alexa Fluor 488
Gene: CCR5
Gene Alias: AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD195 (CCR5)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P51681
Gene Symbols:
CCR5
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1234
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
NP-6G4
Conjugate:
Alexa Fluor 488
Gene:
CCR5
Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD200R3
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q5UKY4
Gene Symbols: CD200R3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 74603
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: Ba13
Conjugate: Alexa Fluor 488
Gene: CD200R3
Gene Alias: 4733401I18Rik; 4833409J19Rik; AI505817; BB106877; CD200 cell surface glycoprotein receptor 3; CD200 cell surface glycoprotein receptor-like 3; CD200 cell surface glycoprotein receptor-like b; CD200 receptor 3; CD200 receptor-like 3; Cd200r3; CD200RLb; cell surface glycoprotein CD200 receptor 3; Cell surface glycoprotein OX2 receptor 3; mCD200RLb
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD200R3
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q5UKY4
Gene Symbols:
CD200R3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
74603
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Ba13
Conjugate:
Alexa Fluor 488
Gene:
CD200R3
Gene Alias:
4733401I18Rik; 4833409J19Rik; AI505817; BB106877; CD200 cell surface glycoprotein receptor 3; CD200 cell surface glycoprotein receptor-like 3; CD200 cell surface glycoprotein receptor-like b; CD200 receptor 3; CD200 receptor-like 3; Cd200r3; CD200RLb; cell surface glycoprotein CD200 receptor 3; Cell surface glycoprotein OX2 receptor 3; mCD200RLb
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 10 mg
Primary or Secondary: __
Target Species: __
Product Type: CORM 3
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
10 mg
Primary or Secondary:
__
Target Species:
__
Product Type:
CORM 3
Isotype:
__
Antigen: CD204
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P30204
Gene Symbols: MSR1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20288
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: M204PA
Conjugate: Alexa Fluor 488
Gene: MSR1
Gene Alias: bovine scavenger receptor type II, CD204, Macrophage acetylated LDL receptor I and II, macrophage scavenger receptor 1, macrophage scavenger receptor type III, macrophage scavenger receptor types I and II, MRS-A, MSR, Msr1, MSR-A, phSR1, phSR2, RGD1564316, SCARA1, Scavenger receptor class A member 1, scavenger receptor class A, member 1, scavenger receptor type A, scavenger receptor type I, Scvr, SRA, SR-A, SR-AI, SR-AI/II, SR-AII
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD204
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P30204
Gene Symbols:
MSR1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20288
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
M204PA
Conjugate:
Alexa Fluor 488
Gene:
MSR1
Gene Alias:
bovine scavenger receptor type II, CD204, Macrophage acetylated LDL receptor I and II, macrophage scavenger receptor 1, macrophage scavenger receptor type III, macrophage scavenger receptor types I and II, MRS-A, MSR, Msr1, MSR-A, phSR1, phSR2, RGD1564316, SCARA1, Scavenger receptor class A member 1, scavenger receptor class A, member 1, scavenger receptor type A, scavenger receptor type I, Scvr, SRA, SR-A, SR-AI, SR-AI/II, SR-AII
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ