Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Kallikrein 3/PSA
0.2mg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Unconjugated
Mouse
Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
354
Recombinant full-length human KLK3 protein
Primary
Store at 4C.
33.5 kDa
KLK3/1248
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Monoclonal
Purified
RUO
Human
APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin
KLK3
IgG1 κ
Protein A or G purified
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.