63-073-942

CD73 Monoclonal Antibody (AD2), Super Bright™ 600, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 63-073-942-Each-of-1 In Stock ₹ 30,288.24

63-073-942 - Each of 1

₹ 30,288.24

In Stock

Quantity

1

Base Price: ₹ 30,288.24

GST (18%): ₹ 5,451.883

Total Price: ₹ 35,740.123

Antigen

CD73

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P21589

Gene Symbols

NT5E

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4907

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

AD2

Conjugate

Super Bright 600

Gene

NT5E

Gene Alias

2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: This AD2 monoclonal antibody reacts with human CD73, a 5'-ectonucleotidase that converts 5'-adenosine monophosphate to adenosine
  • CD73 is expressed on the surface of endothelial cells, as well as B and T cells, including some CD4+Foxp3+ regulatory T cells
  • Adenosine production by these cells has been linked to the inhibition of CD4 T cell effector functions such as proliferation and cytokine secretion
  • CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP
  • CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage
  • CD73 is used as a marker of lymphocyte differentiation
  • Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases
  • Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate
  • The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations
  • Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis
  • Two transcript variants encoding different isoforms of CD73 have been found.

Compare Similar Items

Show Difference

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Invitrogen

63-073-942

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Antigen:
CD73

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21589

Gene Symbols:
NT5E

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4907

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
AD2

Conjugate:
Super Bright 600

Gene:
NT5E

Gene Alias:
2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

eBioscience

63-080-942

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Antigen:
CD80 (B7-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P33681

Gene Symbols:
CD80

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
941

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2D10.4

Conjugate:
Super Bright 600

Gene:
CD80

Gene Alias:
Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

R&D Systems

63-081

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store at -20°C

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
1 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Fischer Scientific

63-086-941

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Antigen:
CD86 (B7-2)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P42081

Gene Symbols:
CD86

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
942

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
IT2.2

Conjugate:
Super Bright 600

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ