Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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TfR (Transferrin R)
0.2 mg/mL
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
7037
Recombinant human extracellular TFRC protein fragment (aa94-212) (exact sequence is proprietary)
Primary
Store at 4C.
TFRC/1818
Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page
Monoclonal
Purified
RUO
Human
CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
TFRC
IgG2b κ
Protein A or G purified
It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.