7092242
CD304 (Neuropilin-1) Monoclonal Antibody (3DS304M), APC, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD304 (Neuropilin-1)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Gene Symbols
NRP1
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
NRP1
Clone
3DS304M
Applications
Flow Cytometry
Conjugate
APC
Host Species
Rat
Target Species
Mouse
Gene Accession No.
P97333
Gene ID (Entrez)
18186
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: The monoclonal antibody 3DS304M recognizes mouse CD304 (Neuropilin-1), a type 1 transmembrane glycoprotein present on the surface of multiple cell types, including: regulatory T cells (Treg), NKT cells, DC, certain types of stem cells, neurons, endothelial cells, and some neoplastic cells
- Neuropilin-1, in complex with plexins, serves as a co-receptor for type 3 semaphorins in growing neurons
- It is also involved in the process of angiogenesis being a part of a functional receptor for VEGF in endothelial cells
- In mice, Neuropilin-1 is expressed on thymus-derived natural Treg but not peripherally induced Treg
- In addition, transient expression on recently activated non-regulatory T cells has been observed
- Neuropilin-1 has been used as a marker of recent thymic emigrants in the mouse iNKT cell population
- It has been shown that Neuropilin-1 forms a complex with TGF beta receptors, activating the latent form of TGF beta (LAP-TGF beta 1) and augmenting canonical Smad2/3 signaling
- This 3DS304M antibody will recognize formaldehyde-fixed as well as methanol-treated epitopes
- Applications Reported: This 3DS304M antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 3DS304M antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.25 μg per test
- Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain
- Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors
- Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system
- This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis
- Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.
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Antigen: CD304 (Neuropilin-1)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Gene Symbols: NRP1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: NRP1
Clone: 3DS304M
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P97333
Gene ID (Entrez): 18186
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD304 (Neuropilin-1)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Gene Symbols:
NRP1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
NRP1
Clone:
3DS304M
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P97333
Gene ID (Entrez):
18186
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: FOXP3
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Gene Symbols: Foxp3
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Foxp3
Clone: PCH101
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rat
Target Species: Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey
Gene Accession No.: Q6U8D7, Q9BZS1
Gene ID (Entrez): 102120882, 50943, 574303, 740909
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
FOXP3
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Gene Symbols:
Foxp3
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Foxp3
Clone:
PCH101
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rat
Target Species:
Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey
Gene Accession No.:
Q6U8D7, Q9BZS1
Gene ID (Entrez):
102120882, 50943, 574303, 740909
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: F4/80
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
Gene Symbols: ADGRE1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: ADGRE1
Clone: BM8
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rat
Target Species: Mouse
Gene Accession No.: Q61549
Gene ID (Entrez): 13733
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
F4/80
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
Gene Symbols:
ADGRE1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
ADGRE1
Clone:
BM8
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
Q61549
Gene ID (Entrez):
13733
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: Armenian Hamster IgG
Concentration: 0.2 mg/mL
Classification: __
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: IgG; Immunoglobulin G; ImmunoglobulinG
Gene Symbols: __
Primary or Secondary: Isotype Control (Primary)
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: __
Clone: eBio299Arm
Applications: Control, Flow Cytometry
Conjugate: APC
Host Species: Armenian Hamster
Target Species: Not Applicable
Gene Accession No.: __
Gene ID (Entrez): __
Isotype: IgG
Purification Method: Affinity chromatography
Product Type: __
Antigen:
Armenian Hamster IgG
Concentration:
0.2 mg/mL
Classification:
__
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
IgG; Immunoglobulin G; ImmunoglobulinG
Gene Symbols:
__
Primary or Secondary:
Isotype Control (Primary)
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
__
Clone:
eBio299Arm
Applications:
Control, Flow Cytometry
Conjugate:
APC
Host Species:
Armenian Hamster
Target Species:
Not Applicable
Gene Accession No.:
__
Gene ID (Entrez):
__
Isotype:
IgG
Purification Method:
Affinity chromatography
Product Type:
__