7092510

CD274 Mouse anti-Human, PE, Clone: MIH1, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD274

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

MIH1

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

B7-H1, PD-L1

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Description

  • PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor
  • They are expressed on immature dendritic cells and mature dendritic cells
  • PD-L1, also called B7-H1, is expressed on antigen-presenting cells, including IFN- γ-stimulated monocytes, and activated human and murine dendritic cells
  • Monoclonal antibodies that block PD-L1 and PD-L2 on dendritic cells result in enhanced T cell proliferation and cytokine production
  • PD-L1 is also expressed on placental trophoblasts, myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas
  • Studies show overlapping functions of PD-L1 and PD-L2 and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.

Compare Similar Items

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Fischer Scientific

7092510

Mouse Monoclonal Antibody...


Antigen:
CD274

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
MIH1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B7-H1, PD-L1

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7092511

Hamster Monoclonal Antibody...


Antigen:
CD279

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
J43

Classification:
Monoclonal

Host Species:
Hamster

Target Species:
Mouse

Isotype:
IgG2 κ

Purification Method:
Affinity Purified

Description:
PD-1

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Mouse Monoclonal Antibody...


Antigen:
CD279

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
MIH4

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

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Antigen:
CD28

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
37.51

Classification:
Monoclonal

Host Species:
Hamster

Target Species:
Mouse

Isotype:
IgG2 λ1

Purification Method:
Affinity Purified

Description:
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