7092564

CD4 Rat anti-Mouse, PE, Clone: GK1.5, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD4

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Rat

Target Species

Mouse

Immunogen

Mouse CTL clone V4

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

GK1.5

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2b κ

Purification Method

Affinity Purified

Description

Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

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Description

  • The GK1.5 monoclonal antibody specifically binds to the mouse CD4 (L3T4) differentiation antigen
  • CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells
  • In addition, CD4 has also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells
  • CD4 has also been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm
  • CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
  • It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck
  • The GK1.5 antibody reportedly blocks binding of the RM4-5 and H129.19, but not RM4-4 mouse CD4-specific antibodies.

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7092564

Rat Monoclonal Antibody...


Antigen:
CD4

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CTL clone V4

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
GK1.5

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

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Antigen:
CD4

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse Thymocytes (BALB/c)

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
RM4-5

Applications:
Flow Cytometry

Conjugate:
PerCP

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

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Antigen:
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Concentration:
__

Classification:
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Host Species:
Mouse

Target Species:
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Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
5C3

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
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Antigen:
CD40

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD40 Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
3/23

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
__