7092567

CD4 Rat anti-Mouse, PerCP, Clone: RM4-5, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD4

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Rat

Target Species

Mouse

Immunogen

Mouse Thymocytes (BALB/c)

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

RM4-5

Applications

Flow Cytometry

Conjugate

PerCP

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

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Description

  • The RM4-5 monoclonal antibody specifically binds to the CD4 (L3T4) differentiation antigen expressed on most thymocytes, subpopulations of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells and immunosuppressive regulatory T cells), and a subset of NK-T cells
  • CD4 has also been reported to be detected on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells
  • CD4 has been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm
  • CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
  • It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck
  • Purified RM4-5 mAb has been reported to block the binding of FITC-conjugated anti-mouse CD4 clones GK1.5 and H129.19, but not the RM4-4 clone.

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Show Difference

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Fischer Scientific

7092567

Rat Monoclonal Antibody...


Antigen:
CD4

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse Thymocytes (BALB/c)

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
RM4-5

Applications:
Flow Cytometry

Conjugate:
PerCP

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

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Antigen:
CD40

Concentration:
__

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
5C3

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
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Antigen:
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Concentration:
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Classification:
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Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD40 Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
3/23

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
__

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Antigen:
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Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD40 Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
3/23

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
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Purification Method:
Affinity Purified

Description:
__