7105406

NKX2.2 Mouse, Clone: SPM564, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

NKX2.2

Dilution

Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B

Gene Symbols

NKX2-2

Isotype

IgG2b κ

Purification Method

Protein A purified

Test Specificity

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Clone

SPM564

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Mouse, Rat, Chicken

Gene Accession No.

O95096

Gene ID (Entrez)

4821

Immunogen

Human NKX2.2 recombinant protein

Primary or Secondary

Primary

Content And Storage

Store at 4C.

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Description

  • NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Img

Fischer Scientific

7105406

Mouse Monoclonal Antibody...


Antigen:
NKX2.2

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B

Gene Symbols:
NKX2-2

Isotype:
IgG2b κ

Purification Method:
Protein A purified

Test Specificity:
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Clone:
SPM564

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Rat, Chicken

Gene Accession No.:
O95096

Gene ID (Entrez):
4821

Immunogen:
Human NKX2.2 recombinant protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Img

Fischer Scientific

7105407

Mouse Monoclonal Antibody has been ...


Antigen:
Ornithine Decarboxylase

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page, Immunofluorescence

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1

Gene Symbols:
ODC1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Clone:
ODC1/485

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
P11926

Gene ID (Entrez):
4953

Immunogen:
Recombinant human ODC-1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Img

Fischer Scientific

7105407

Mouse Monoclonal Antibody has been ...


Antigen:
Ornithine Decarboxylase

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page, Immunofluorescence

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1

Gene Symbols:
ODC1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Clone:
ODC1/485

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
P11926

Gene ID (Entrez):
4953

Immunogen:
Recombinant human ODC-1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Img

Fischer Scientific

7105408

Mouse Monoclonal Antibody...


Antigen:
Ornithine Decarboxylase

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1

Gene Symbols:
ODC1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Clone:
SPM565

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
P11926

Gene ID (Entrez):
4953

Immunogen:
Recombinant human ODC-1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.