7121097
CD7 Mouse anti-Human, Clone: T3-3A1, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD7
Dilution
Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Alias
CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Gene Symbols
CD7
Isotype
IgG1 κ
Purification Method
Protein A or G purified
Test Specificity
Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Clone
T3-3A1
Applications
Flow Cytometry, Immunofluorescence
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Cytokine Research, Signal Transduction
Formulation
10mM PBS with No Preservative
Gene ID (Entrez)
924
Immunogen
Human T cells
Primary or Secondary
Primary
Content And Storage
Store at 4°C.
Molecular Weight of Antigen
40 kDa
Related Products
Description
- CD7 Monoclonal specifically detects CD7 in Human samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence, CyTOF-ready.
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Antigen: CD7
Dilution: Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Gene Symbols: CD7
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Clone: T3-3A1
Applications: Flow Cytometry, Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cytokine Research, Signal Transduction
Formulation: 10mM PBS with No Preservative
Gene ID (Entrez): 924
Immunogen: Human T cells
Primary or Secondary: Primary
Content And Storage: Store at 4°C.
Molecular Weight of Antigen: 40 kDa
Antigen:
CD7
Dilution:
Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Gene Symbols:
CD7
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Clone:
T3-3A1
Applications:
Flow Cytometry, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytokine Research, Signal Transduction
Formulation:
10mM PBS with No Preservative
Gene ID (Entrez):
924
Immunogen:
Human T cells
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C.
Molecular Weight of Antigen:
40 kDa
Antigen: CIITA
Dilution: Western Blot 1-2 ug/ml, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 20 ug/ml, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Methylated DNA Immunoprecipitation 1:10-1:1000
Classification: Polyclonal
Form: __
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Gene Alias: C2TA, C2TAMHC class II transactivator type III, CIITAIV, class II, major histocompatibility complex, transactivator, MHC class II transactivator, MHC2TANLR family, acid domain containing, NLRA, nucleotide-binding oligomerization domain, leucine rich repeat and acid domaincontaining
Gene Symbols: CIITA
Isotype: IgG
Purification Method: Affinity Purified
Test Specificity: __
Clone: __
Applications: Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Conjugate: Unconjugated
Host Species: Rabbit
Research Discipline: __
Formulation: PBS with 0.02% Sodium Azide
Gene ID (Entrez): 4261
Immunogen: Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CIITA. The immunogen is located within amino acids 120 - 170 of CIITA.
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: 125 kDa
Antigen:
CIITA
Dilution:
Western Blot 1-2 ug/ml, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 20 ug/ml, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Methylated DNA Immunoprecipitation 1:10-1:1000
Classification:
Polyclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Gene Alias:
C2TA, C2TAMHC class II transactivator type III, CIITAIV, class II, major histocompatibility complex, transactivator, MHC class II transactivator, MHC2TANLR family, acid domain containing, NLRA, nucleotide-binding oligomerization domain, leucine rich repeat and acid domaincontaining
Gene Symbols:
CIITA
Isotype:
IgG
Purification Method:
Affinity Purified
Test Specificity:
__
Clone:
__
Applications:
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Conjugate:
Unconjugated
Host Species:
Rabbit
Research Discipline:
__
Formulation:
PBS with 0.02% Sodium Azide
Gene ID (Entrez):
4261
Immunogen:
Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CIITA. The immunogen is located within amino acids 120 - 170 of CIITA.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
125 kDa
Antigen: HINT2
Dilution: Western Blot 1:1000, Flow Cytometry 1:10-1:1000, ELISA, Immunocytochemistry/Immunofluorescence 1:100
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Gene Alias: EC 3.-, HINT-2, HINT-3, histidine triad nucleotide binding protein 2, histidine triad nucleotide-binding protein 2, mitochondrial, HIT-17, HIT-17kDa, PKCI-1-related HIT protein, protein kinase C inhibitor-2
Gene Symbols: HINT2
Isotype: IgG1 κ
Purification Method: Protein A purified
Test Specificity: __
Clone: 5B10
Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: __
Formulation: Liquid. In PBS (pH 7.4), 10% Glycerol with 0.02% Sodium Azide
Gene ID (Entrez): 84681
Immunogen: Recombinant human HINT2 (18-163aa) purified from E. coli
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: __
Antigen:
HINT2
Dilution:
Western Blot 1:1000, Flow Cytometry 1:10-1:1000, ELISA, Immunocytochemistry/Immunofluorescence 1:100
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Gene Alias:
EC 3.-, HINT-2, HINT-3, histidine triad nucleotide binding protein 2, histidine triad nucleotide-binding protein 2, mitochondrial, HIT-17, HIT-17kDa, PKCI-1-related HIT protein, protein kinase C inhibitor-2
Gene Symbols:
HINT2
Isotype:
IgG1 κ
Purification Method:
Protein A purified
Test Specificity:
__
Clone:
5B10
Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
__
Formulation:
Liquid. In PBS (pH 7.4), 10% Glycerol with 0.02% Sodium Azide
Gene ID (Entrez):
84681
Immunogen:
Recombinant human HINT2 (18-163aa) purified from E. coli
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
__
Antigen: Otubain-1
Dilution: Western Blot 1:1000, Flow Cytometry 1:10-1:1000, ELISA, Immunocytochemistry/Immunofluorescence 1:100
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: Deubiquitinating enzyme OTUB1, EC 3.1.2, EC 3.4.19.12, FLJ20113, FLJ40710, hOTU1, MGC111158, OTB1MGC4584, OTU domain, ubiquitin aldehyde binding 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, OTU1OTU-domain Ubal-binding 1, otubain-1, ubiquitin thioesterase OTUB1, ubiquitin-specific protease otubain 1, Ubiquitin-specific-processing protease OTUB1
Gene Symbols: OTUB1
Isotype: IgG1 κ
Purification Method: Protein A purified
Test Specificity: __
Clone: 170000000000
Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: __
Formulation: Liquid. In PBS (pH 7.4), 10% Glycerol with 0.02% Sodium Azide
Gene ID (Entrez): 55611
Immunogen: Recombinant human OTUB1 (1-271aa) purified from E. coli
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen: __
Antigen:
Otubain-1
Dilution:
Western Blot 1:1000, Flow Cytometry 1:10-1:1000, ELISA, Immunocytochemistry/Immunofluorescence 1:100
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
Deubiquitinating enzyme OTUB1, EC 3.1.2, EC 3.4.19.12, FLJ20113, FLJ40710, hOTU1, MGC111158, OTB1MGC4584, OTU domain, ubiquitin aldehyde binding 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, OTU1OTU-domain Ubal-binding 1, otubain-1, ubiquitin thioesterase OTUB1, ubiquitin-specific protease otubain 1, Ubiquitin-specific-processing protease OTUB1
Gene Symbols:
OTUB1
Isotype:
IgG1 κ
Purification Method:
Protein A purified
Test Specificity:
__
Clone:
170000000000
Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
__
Formulation:
Liquid. In PBS (pH 7.4), 10% Glycerol with 0.02% Sodium Azide
Gene ID (Entrez):
55611
Immunogen:
Recombinant human OTUB1 (1-271aa) purified from E. coli
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
__