7162891
BASE-tag, Mouse anti-Virus, Clone: 7C7, Millipore Sigma™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
BASE-tag
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Virus
Gene Alias
Capsid protein VP1;Capsid protein AVV9
Immunogen
Empty Adeno-associated virus 9 (AAV9) Capsids
Primary or Secondary
Primary
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Clone
7C7
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Inflammation & Immunology
Formulation
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
Cap
Isotype
IgG2b κ
Purification Method
Protein G purified
Test Specificity
Clone 7C7 is a mouse monoclonal antibody that detects various serotypes of Adeno-associated virus (AVV). It targets an epitope with in 14 amino acids from the N-terminal region.
Related Products
Description
- Anti-BASE-tag, clone 7C7, Cat
- No
- MAB131884, is a mouse monoclonal antibody that recognizes the epitope QPAKKRLNFGQTGD and has been tested for use in Western Blotting, Immunoprecipitation, and Immunofluorescence
- Capsid protein VP1 (UniProt: Q6JC40) is encoded by the Cap gene in Adeno-associated virus 9 (AAV9)
- Adeno-associated viruses (AAV) are small non-enveloped DNA viruses that can serve as promising viral vectors for gene delivery, but can also elicits cellular and humoral immune responses
- AAVs are reported to be nonpathogenic in humans and animals and display low immunogenicity
- Following their attachment to cell surface receptor they are internalized via endocytosis and their intracellular trafficking is a rate-limiting, slow and inefficient process
- AAVs contain an icosahedral capsid, which is 22 to 26 nm in diameter
- They are shown to have a single-stranded DNA genome of approximately 4.7 kilobases that is flanked by two T-shaped inverted terminal repeats (ITRs)
- The 7C7 an epitope-tag antibody recognizes a basic ten amino acid epitope (QPAKKRLNFGQTGD) with high specificity
- The basic nature of the BASE-tag epitope sequence distinguishes it from other commonly used epitope tags, such as Myc, EQKLISEEDL, FLAG, DYKDDDDK, HA, YPYDVPDYA, V5 etc
- Clone 7C7 recognizes capsid proteins VP1 and VP2, but not VP3
- Based on sequence identity of the epitope sequence, this antibody is expected to recognize VP1 and VP2 of AAV serotypes 1,2,3,6,7,8, and 9
- (Ref.: Nonnenmacher, M., and Weber, T (2012)
- Gene Ther
- 19(6); 649-658).
Compare Similar Items
Show Difference
Antigen: BASE-tag
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Virus
Gene Alias: Capsid protein VP1;Capsid protein AVV9
Immunogen: Empty Adeno-associated virus 9 (AAV9) Capsids
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 7C7
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Inflammation & Immunology
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: Cap
Isotype: IgG2b κ
Purification Method: Protein G purified
Test Specificity: Clone 7C7 is a mouse monoclonal antibody that detects various serotypes of Adeno-associated virus (AVV). It targets an epitope with in 14 amino acids from the N-terminal region.
Antigen:
BASE-tag
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Virus
Gene Alias:
Capsid protein VP1;Capsid protein AVV9
Immunogen:
Empty Adeno-associated virus 9 (AAV9) Capsids
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
7C7
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Inflammation & Immunology
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
Cap
Isotype:
IgG2b κ
Purification Method:
Protein G purified
Test Specificity:
Clone 7C7 is a mouse monoclonal antibody that detects various serotypes of Adeno-associated virus (AVV). It targets an epitope with in 14 amino acids from the N-terminal region.
Antigen: Reovirus Type 3 sigma 1 hemagglutinin
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Virus
Gene Alias: T3 sigma 1;Reovirus T3 sigma 1
Immunogen: Purified reovirus type 3 virons.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 9BG5
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Inflammation & Immunology
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: N/A
Isotype: IgG2a κ
Purification Method: Protein G purified
Test Specificity: __
Antigen:
Reovirus Type 3 sigma 1 hemagglutinin
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Virus
Gene Alias:
T3 sigma 1;Reovirus T3 sigma 1
Immunogen:
Purified reovirus type 3 virons.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
9BG5
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Inflammation & Immunology
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
N/A
Isotype:
IgG2a κ
Purification Method:
Protein G purified
Test Specificity:
__
Antigen: PD-L1 B7-H1
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: Programmed cell death 1 ligand 1;PDCD1 ligand 1;Programmed death ligand 1;B7 homolog 1;B7-H1;CD274
Immunogen: Recombinant fragment corresponding to the extracellular domain of Mouse Programmed cell death 1 ligand 1.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Clone: 10B5
Conjugate: Unconjugated
Host Species: Armenian Hamster
Research Discipline: Apoptosis & Cancer
Formulation: Purified armenian hamster monoclonal antibody IgG2-IgG3 in PBS without azide.
Gene Symbols: Cd274;B7h1;Pdcd1l1;Pdcd1lg1;Pdl1
Isotype: __
Purification Method: Protein G purified
Test Specificity: This Armenian hamster monoclonal antibody detects Programmed cell death 1 ligand 1 (PD-L1) in murine species.
Antigen:
PD-L1 B7-H1
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
Programmed cell death 1 ligand 1;PDCD1 ligand 1;Programmed death ligand 1;B7 homolog 1;B7-H1;CD274
Immunogen:
Recombinant fragment corresponding to the extracellular domain of Mouse Programmed cell death 1 ligand 1.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Clone:
10B5
Conjugate:
Unconjugated
Host Species:
Armenian Hamster
Research Discipline:
Apoptosis & Cancer
Formulation:
Purified armenian hamster monoclonal antibody IgG2-IgG3 in PBS without azide.
Gene Symbols:
Cd274;B7h1;Pdcd1l1;Pdcd1lg1;Pdl1
Isotype:
__
Purification Method:
Protein G purified
Test Specificity:
This Armenian hamster monoclonal antibody detects Programmed cell death 1 ligand 1 (PD-L1) in murine species.
Antigen: PD-L1 B7-H1
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse
Gene Alias: Programmed cell death 1 ligand 1;PDCD1 ligand 1;Programmed death ligand 1;B7 homolog 1;B7-H1;CD274
Immunogen: Recombinant fragment corresponding to the extracellular domain of Mouse Programmed cell death 1 ligand 1.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Clone: 10B5
Conjugate: Unconjugated
Host Species: Armenian Hamster
Research Discipline: Apoptosis & Cancer
Formulation: Purified armenian hamster monoclonal antibody IgG2-IgG3 in PBS without azide.
Gene Symbols: Cd274;B7h1;Pdcd1l1;Pdcd1lg1;Pdl1
Isotype: __
Purification Method: Protein G purified
Test Specificity: This Armenian hamster monoclonal antibody detects Programmed cell death 1 ligand 1 (PD-L1) in murine species.
Antigen:
PD-L1 B7-H1
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse
Gene Alias:
Programmed cell death 1 ligand 1;PDCD1 ligand 1;Programmed death ligand 1;B7 homolog 1;B7-H1;CD274
Immunogen:
Recombinant fragment corresponding to the extracellular domain of Mouse Programmed cell death 1 ligand 1.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Clone:
10B5
Conjugate:
Unconjugated
Host Species:
Armenian Hamster
Research Discipline:
Apoptosis & Cancer
Formulation:
Purified armenian hamster monoclonal antibody IgG2-IgG3 in PBS without azide.
Gene Symbols:
Cd274;B7h1;Pdcd1l1;Pdcd1lg1;Pdl1
Isotype:
__
Purification Method:
Protein G purified
Test Specificity:
This Armenian hamster monoclonal antibody detects Programmed cell death 1 ligand 1 (PD-L1) in murine species.