7162964
mPEG, Mouse anti-All, Clone: 15-2b, Millipore Sigma™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
mPEG
Applications
ELISA
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Signaling
Formulation
Purified mouse monoclonal antibody IgG2b in PBS with 0.04% sodium azide.
Immunogen
Methoxy PEG covalently conjugated to E.coli beta-glucuronidase.
Primary or Secondary
Primary
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Clone
15-2b
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
All species
Gene Alias
Methoxy polyethylene glycol
Isotype
IgG2b κ
Purification Method
Protein A purified
Test Specificity
Clone 15-2b specifically detects proteins conjugated with methoxy polyethylene glycol (mPEG).
Description
- Anti-mPEG, clone 15-2b, Cat
- No
- MABS2002, is a mouse monoclonal antibody that detects methoxy-PEG (mPEG)-conjugated proteins and has been tested for use in ELISA
- Polyethylene glycols (PEG) are non-toxic, uncharged, hydrophilic long chain polymers with a big exclusion volume in aqueous solutions
- The covalent attachment of PEG is commonly employed to modify proteins and drugs that can increase their bioavailability and reduce immunogenicity and proteolytic degradation
- The monomethoxylated form of polyethylene glycol (mPEG) has been widely employed in drug modifications
- mPEG modification reduces nonspecific binding and prevents recognition by the reticuloendothelial system
- This monoclonal antibody (clone 15-2b) specifically binds to the terminal methoxy group, but not the backbone of PEG
- It displays high affinity for the terminal methoxy group and can be easily used as a detection antibody for the quantification of mPEG by ELISA
- It is also suitable for detection of PEGylated liposomes and nanoparticles
- The mPEG cell-based competition ELISA can detect lower molecular-weight (< 2 kDa) mPEG molecules even at nanomolar concentration and the assay is not affected by the presence of mouse or human serum
- In addition, mPEG cell-based ELISA can be useful in determining the pharmacokinetics of a mPEG molecule an animal without the need for any radiolabeling.
Compare Similar Items
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Antigen: mPEG
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Signaling
Formulation: Purified mouse monoclonal antibody IgG2b in PBS with 0.04% sodium azide.
Immunogen: Methoxy PEG covalently conjugated to E.coli beta-glucuronidase.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 15-2b
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: All species
Gene Alias: Methoxy polyethylene glycol
Isotype: IgG2b κ
Purification Method: Protein A purified
Test Specificity: Clone 15-2b specifically detects proteins conjugated with methoxy polyethylene glycol (mPEG).
Antigen:
mPEG
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Signaling
Formulation:
Purified mouse monoclonal antibody IgG2b in PBS with 0.04% sodium azide.
Immunogen:
Methoxy PEG covalently conjugated to E.coli beta-glucuronidase.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
15-2b
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
All species
Gene Alias:
Methoxy polyethylene glycol
Isotype:
IgG2b κ
Purification Method:
Protein A purified
Test Specificity:
Clone 15-2b specifically detects proteins conjugated with methoxy polyethylene glycol (mPEG).
Antigen: EphA2
Applications: Flow Cytometry, Immunoprecipitation, Inhibition Assays
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Signaling
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen: KP-2, KP-3, SUIT-2, and MIAPaCa-2 cells.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: F2-27
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: Ephrin type-A receptor 2;EC: 2.7.10.1;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: Clone F2-27 specifically detects Ephrin type -A receptor 2 in human.
Antigen:
EphA2
Applications:
Flow Cytometry, Immunoprecipitation, Inhibition Assays
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Signaling
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen:
KP-2, KP-3, SUIT-2, and MIAPaCa-2 cells.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
F2-27
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
Ephrin type-A receptor 2;EC: 2.7.10.1;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
Clone F2-27 specifically detects Ephrin type -A receptor 2 in human.
Antigen: SREBP-1
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Signaling
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen: His-tagged recombinant fragment corresponding to 107 amino acids from the N-terminal half of human Sterol regulatory element-binding protein 1 (SREBP-1).
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: 2A4
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Hamster, Canine, Human
Gene Alias: Sterol regulatory element-binding protein 1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory element-binding transcription factor 1
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: Clone 2A4 is a mouse monoclonal antibody that detects Sterol regulatory element-binding protein 1. It targets an epitope within 107 amino acids from the N-terminal half.
Antigen:
SREBP-1
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Signaling
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen:
His-tagged recombinant fragment corresponding to 107 amino acids from the N-terminal half of human Sterol regulatory element-binding protein 1 (SREBP-1).
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
2A4
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Hamster, Canine, Human
Gene Alias:
Sterol regulatory element-binding protein 1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory element-binding transcription factor 1
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
Clone 2A4 is a mouse monoclonal antibody that detects Sterol regulatory element-binding protein 1. It targets an epitope within 107 amino acids from the N-terminal half.
Antigen: GCP2
Applications: ELISA, Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cell Structure
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen: GST-tagged recombinant fragment corresponding to the first 194 amino acids from the N-terminal region of murine Gamma-tubulin complex component 2.
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Clone: GCP2-02
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Mouse, Chicken, Human, Frog, Fish
Gene Alias: Gamma-tubulin complex component 2
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: Clone GCP2-02 specifically detects GCP2 in T98G glioblastoma cells. It targets an epitope within 12 amino acids from the N-terminal region.
Antigen:
GCP2
Applications:
ELISA, Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cell Structure
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen:
GST-tagged recombinant fragment corresponding to the first 194 amino acids from the N-terminal region of murine Gamma-tubulin complex component 2.
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Clone:
GCP2-02
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Mouse, Chicken, Human, Frog, Fish
Gene Alias:
Gamma-tubulin complex component 2
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
Clone GCP2-02 specifically detects GCP2 in T98G glioblastoma cells. It targets an epitope within 12 amino acids from the N-terminal region.