7189017
STAT3 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
STAT3
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P40763
Gene ID (Entrez)
6774
Immunogen
This antibody was raised against a peptide within the N-terminal region of human STAT3.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
STAT3
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols
STAT3
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
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Antigen: STAT3
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P40763
Gene ID (Entrez): 6774
Immunogen: This antibody was raised against a peptide within the N-terminal region of human STAT3.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: STAT3
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols: STAT3
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
STAT3
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P40763
Gene ID (Entrez):
6774
Immunogen:
This antibody was raised against a peptide within the N-terminal region of human STAT3.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
STAT3
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols:
STAT3
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: Histone H3, C-terminal
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P68431, P84243, Q6NXT2, Q71DI3
Gene ID (Entrez): 126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968
Immunogen: This Histone H3, C-terminal antibody was raised against a C-terminal peptide of histone H3.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: H3-3A
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: BOS_13790; BOS_15646; BOS_15671; BOS_19479; BUR5; CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; h3; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; h3f3a; H3F3B; h3f3b.1; H3F3C; h3f3d;
Gene Symbols: H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7
Isotype: IgG
Purification Method: __
Product Type: Antibody
Antigen:
Histone H3, C-terminal
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3
Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968
Immunogen:
This Histone H3, C-terminal antibody was raised against a C-terminal peptide of histone H3.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
H3-3A
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
BOS_13790; BOS_15646; BOS_15671; BOS_19479; BUR5; CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; h3; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; h3f3a; H3F3B; h3f3b.1; H3F3C; h3f3d;
Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7
Isotype:
IgG
Purification Method:
__
Product Type:
Antibody
Antigen: MAD2L1
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: Q13257, Q9Z1B5
Gene ID (Entrez): 4085, 56150
Immunogen: This MAD2L1 antibody was raised against full-length recombinant human MAD2L1.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MAD2L1
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: AA673185; HsMAD2; MAD2; MAD2 (mitotic arrest deficient, homolog)-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2 mitotic arrest deficient-like 1; MAD2 mitotic arrest deficient-like 1 (yeast); Mad2a; Mad2l1; MAD2-like 1; MAD2-like protein 1; MadL1; Mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; Mitotic spindle assembly checkpoint protein MAD2A
Gene Symbols: MAD2L1
Isotype: IgG1
Purification Method: Protein G
Product Type: Antibody
Antigen:
MAD2L1
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
Q13257, Q9Z1B5
Gene ID (Entrez):
4085, 56150
Immunogen:
This MAD2L1 antibody was raised against full-length recombinant human MAD2L1.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MAD2L1
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
AA673185; HsMAD2; MAD2; MAD2 (mitotic arrest deficient, homolog)-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2 mitotic arrest deficient-like 1; MAD2 mitotic arrest deficient-like 1 (yeast); Mad2a; Mad2l1; MAD2-like 1; MAD2-like protein 1; MadL1; Mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; Mitotic spindle assembly checkpoint protein MAD2A
Gene Symbols:
MAD2L1
Isotype:
IgG1
Purification Method:
Protein G
Product Type:
Antibody
Antigen: c-Myc
Applications: Gel Shift, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human
Gene Accession No.: P01106
Gene ID (Entrez): 4609
Immunogen: This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MYC
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols: MYC
Isotype: IgG2a
Purification Method: Protein G
Product Type: Antibody
Antigen:
c-Myc
Applications:
Gel Shift, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
P01106
Gene ID (Entrez):
4609
Immunogen:
This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MYC
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols:
MYC
Isotype:
IgG2a
Purification Method:
Protein G
Product Type:
Antibody