7218497
CD102 (ICAM-2) Monoclonal Antibody (3C4 (mIC2/4)), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD102 (ICAM-2)
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with no preservative; pH 7.2
Gene Alias
CD102; Icam2; ICAM-2; Intercellular adhesion molecule 2; Ly-60; Lymphocyte function-associated AG-1 counter-receptor; RP23-418O11.10-001
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Product Type
Antibody
Clone
3C4 (mIC2/4)
Applications
Flow Cytometry, Functional Assay
Conjugate
Functional Grade
Host Species
Rat
Target Species
Mouse
Gene Accession No.
P35330
Gene ID (Entrez)
15896
Primary or Secondary
Primary
Content And Storage
4° C
Gene
ICAM2
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Description
- Description: The monoclonal antibody 3C4 (mIC2/4) recognizes mouse CD102, also known as intercellular adhesion molecule-2 (ICAM-2)
- CD102, a member of the Immunoglobulin superfamily of receptors with 2 extracellular Ig domains, binds LFA (CD11a/CD18) and Mac-1 (CD11b/CD18), thereby mediating cellular interactions to lymphocytes
- CD102 plays a role in NK cytotoxicity and migration, and lymphocyte recirculation
- Expression of CD102 is found on most lymphocytes, monocytes and platelets
- The 3C4 (mIC2/4) antibody blocks interaction of lymphocytes with antigen presenting cells
- Applications Reported: This 3C4 (mIC2/4) antibody has been reported for use in flow cytometric analysis and functional assays
- Applications Tested: This 3C4 (mIC2/4) antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Storage and handling: Use in a sterile environment
- Filtration: 0.2 μm post-manufacturing filtered
- Purity: Greater than 90%, as determined by SDS-PAGE
- Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
- Aggregation: Less than 10%, as determined by HPLC
- ICAM-2 is a member of the intercellular adhesion molecule (ICAM) family
- All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein
- ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion
- It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance
- Several transcript variants encoding the same protein have been found for this gene
- Diseases associated with ICAM2 include Colon Carcinoma In Situ.
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Antigen: CD102 (ICAM-2)
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.2
Gene Alias: CD102; Icam2; ICAM-2; Intercellular adhesion molecule 2; Ly-60; Lymphocyte function-associated AG-1 counter-receptor; RP23-418O11.10-001
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Clone: 3C4 (mIC2/4)
Applications: Flow Cytometry, Functional Assay
Conjugate: Functional Grade
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P35330
Gene ID (Entrez): 15896
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: ICAM2
Antigen:
CD102 (ICAM-2)
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.2
Gene Alias:
CD102; Icam2; ICAM-2; Intercellular adhesion molecule 2; Ly-60; Lymphocyte function-associated AG-1 counter-receptor; RP23-418O11.10-001
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Clone:
3C4 (mIC2/4)
Applications:
Flow Cytometry, Functional Assay
Conjugate:
Functional Grade
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P35330
Gene ID (Entrez):
15896
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
ICAM2
Antigen: Cytokeratin 18
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: __
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Clone: LDK18
Applications: __
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P05783
Gene ID (Entrez): 3875
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: KRT18
Antigen:
Cytokeratin 18
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
__
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Clone:
LDK18
Applications:
__
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P05783
Gene ID (Entrez):
3875
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
KRT18
Antigen: CD254 (RANK Ligand)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Clone: MIH24
Applications: ELISA, Flow Cytometry
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: O14788
Gene ID (Entrez): 8600
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: TNFSF11
Antigen:
CD254 (RANK Ligand)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Clone:
MIH24
Applications:
ELISA, Flow Cytometry
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
O14788
Gene ID (Entrez):
8600
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
TNFSF11
Antigen: CD101
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: __
Gene Alias: Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Isotype: IgG1
Purification Method: Affinity chromatography
Product Type: Antibody
Clone: BB27
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q93033
Gene ID (Entrez): 9398
Primary or Secondary: Primary
Content And Storage: __
Gene: CD101
Antigen:
CD101
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
__
Gene Alias:
Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Isotype:
IgG1
Purification Method:
Affinity chromatography
Product Type:
Antibody
Clone:
BB27
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q93033
Gene ID (Entrez):
9398
Primary or Secondary:
Primary
Content And Storage:
__
Gene:
CD101