ABC481MI
MilliporeSigma™ Rabbit anti-Cytosolic 5'-nucleotidase II, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC481MI-Each-of-1 | In Stock | ₹ 39,063.27 |
ABC481MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,063.27
GST (18%): ₹ 7,031.389
Total Price: ₹ 46,094.659
Antigen
Cytosolic 5'-nucleotidase II
Classification
Polyclonal
Gene Accession No.
P49902
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Applications
Immunohistochemistry, Western Blot
Formulation
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
NT5C2; NT5B; NT5CP; PNT5
Immunogen
KLH-conjugated linear peptide corresponding to human Cytosolic 5'-nucleotidase II near the C-terminus.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001127845
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Related Products
Description
- Specifically detects Cytosolic 5'-nucleotidase II in Human samples, and it is validated for Immunohistochemistry, Western Blotting Cytosolic purine 5'-nucleotidase (EC 3.1.3.5; UniProt P49902; also known as 5'-nucleotidase (purine), cytosolic type B, Cytosolic 5'-nucleotidase II, IMP-specific 5'-NT, Purine 5' nucleotidase) is encoded by the NT5C2 (also known as cN-II, GMP, NT5B, NT5CP, PNT5, SPG45, SPG65) gene (Entrez Gene ID 22978) in human
- NT5C2 protein is a cytosolic enzyme that catalyzes the hydrolysis of inosine 5'-monophosphate (IMP) and other purine nucleotides into the corresponding ribonucleoside and a phosphate
- Purine nucleotides are neuroprotective and play a critical role in the ischemic and developing brain, alterations in purine nucleotides levels could sensitize neurons to stress and insult
- Hereditary spastic paraplegias (HSPs) are neurodegenerative motor neuron diseases characterized by progressive age-dependent loss of corticospinal motor tract function
- Mutations in NT5C2 and several other genes coding for purine nucleotide metabolizing enzymes are linked to autosomal recessive HSP (AR-HSP) in a study of 55 families displaying AR-HSP (PMID 24482476).
Compare Similar Items
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Antigen: Cytosolic 5'-nucleotidase II
Classification: Polyclonal
Gene Accession No.: P49902
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: NT5C2; NT5B; NT5CP; PNT5
Immunogen: KLH-conjugated linear peptide corresponding to human Cytosolic 5'-nucleotidase II near the C-terminus.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001127845
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
Cytosolic 5'-nucleotidase II
Classification:
Polyclonal
Gene Accession No.:
P49902
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
NT5C2; NT5B; NT5CP; PNT5
Immunogen:
KLH-conjugated linear peptide corresponding to human Cytosolic 5'-nucleotidase II near the C-terminus.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001127845
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: Gumby
Classification: Polyclonal
Gene Accession No.: Q96BN8
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: OTULIN; FAM105B
Immunogen: GST-tagged recombinant protein corresponding to human Gumby.
Quantity: 100 μL
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_612357
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
Gumby
Classification:
Polyclonal
Gene Accession No.:
Q96BN8
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
OTULIN; FAM105B
Immunogen:
GST-tagged recombinant protein corresponding to human Gumby.
Quantity:
100 μL
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_612357
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: BCL2A1/BFL-1
Classification: Polyclonal
Gene Accession No.: Q16548
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Immunohistochemistry, Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Immunogen: KLH-conjugated linear peptide corresponding to the near N-terminal of human BCL2A1/BFL-1.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001108207
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
BCL2A1/BFL-1
Classification:
Polyclonal
Gene Accession No.:
Q16548
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Immunohistochemistry, Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Immunogen:
KLH-conjugated linear peptide corresponding to the near N-terminal of human BCL2A1/BFL-1.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001108207
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: Caspase 3
Classification: Polyclonal
Gene Accession No.: P42574
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Applications: Immunocytochemistry, Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CASP3, CPP32
Immunogen: KLH-conjugated linear peptide corresponding to human Caspase 3 near the C-terminus.
Quantity: 50 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_004337
Content And Storage: 2°C to 8°C for one year
Antigen:
Caspase 3
Classification:
Polyclonal
Gene Accession No.:
P42574
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Applications:
Immunocytochemistry, Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CASP3, CPP32
Immunogen:
KLH-conjugated linear peptide corresponding to human Caspase 3 near the C-terminus.
Quantity:
50 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_004337
Content And Storage:
2°C to 8°C for one year