ABC488MI

MilliporeSigma™ Rabbit anti-Gumby, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABC488MI-Each-of-1 In Stock ₹ 41,307.51

ABC488MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

Gumby

Classification

Polyclonal

Gene Accession No.

Q96BN8

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Applications

Western Blot

Formulation

Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

OTULIN; FAM105B

Immunogen

GST-tagged recombinant protein corresponding to human Gumby.

Quantity

100 μL

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_612357

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects Gumby in Human samples, and it is validated for Western Blotting Ubiquitin thioesterase otulin (EC:3.4.19.12; UniProt Q96BN8), also known as Deubiquitinating enzyme otulin, Gumby, OTU domain-containing deubiquitinase with linear linkage specificity, Protein FAM105B, Ubiquitin thioesterase Gumby), is encoded by the OTULIN gene in murine species
  • Gumby belongs to the ovarian tumour (OTU) domain-containing protease family of deubiquitinases (DUBs) that catalyze the removal of ubiquitins from ubiquitinated proteins
  • Gumby is reported to associate with linear ubiquitin assembly complex (LUBAC) and counteract LUBAC activity by removing linear ('Met-1'-linked) polyubiquitin chains from substrate proteins
  • The gumby–LUBAC axis plays an important role in angiogenesis, craniofacial and neuronal development by regulating canonical Wnt signalling.

Compare Similar Items

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MilliporeSigma™

ABC488MI

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Antigen:
Gumby

Classification:
Polyclonal

Gene Accession No.:
Q96BN8

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
OTULIN; FAM105B

Immunogen:
GST-tagged recombinant protein corresponding to human Gumby.

Quantity:
100 μL

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_612357

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Img

MilliporeSigma™

ABC490MI

--


Antigen:
BCL2A1/BFL-1

Classification:
Polyclonal

Gene Accession No.:
Q16548

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
BCL2A1; BCL2L5; BFL1; GRS; HBPA1

Immunogen:
KLH-conjugated linear peptide corresponding to the near N-terminal of human BCL2A1/BFL-1.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_001108207

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Img

MilliporeSigma™

ABC495MI

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Antigen:
Caspase 3

Classification:
Polyclonal

Gene Accession No.:
P42574

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Applications:
Immunocytochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CASP3, CPP32

Immunogen:
KLH-conjugated linear peptide corresponding to human Caspase 3 near the C-terminus.

Quantity:
50 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_004337

Content And Storage:
2°C to 8°C for one year

Img

MilliporeSigma

ABC498MI

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Antigen:
BCL2A1/BFL-1

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.

Gene Symbols:
BCL2A1; BCL2L5; BFL1; GRS; HBPA1

Immunogen:
Recombinant protein corresponding to human BCL2A1/BFL-1.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
NP_001108207

Content And Storage:
-20°C in undiluted aliquots for up to 12 months, Avoid Freeze/Thaw Cycles