ABE1379MI

MilliporeSigma™ Rabbit anti-F-box/WD repeat-containing protein 7, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABE1379MI-Each-of-1 In Stock ₹ 38,734.72

ABE1379MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

F-box/WD repeat-containing protein 7

Classification

Polyclonal

Gene Accession No.

Q969H0

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Applications

Immunohistochemistry, Western Blot

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

FBXW7; FBW7; FBX30; SEL10

Immunogen

KLH-conjugated linear peptide corresponding to human F-box/WD repeat-containing protein 7.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NP_060785

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects F-box/WD repeat-containing protein 7 in Human samples, and it is validated for Immunohistochemistry, Western Blotting F-box/WD repeat-containing protein 7 (UniProt Q969H0; also known as Archipelago, F-box and WD-40 domain protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, hAgo, hCdc4, Homolog of C elegans sel-10) is encoded by the FBXW7 (also known as AGO, CDC4, FBW7, FBX30, SEL10) gene (Gene ID 55294) in human
  • Polyubiquitination of proteins is mediated by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s)
  • There exist RING finger-type, HECT-type, and U-box type of E3 ligases
  • The F-box/WD repeat-containing protein 7 functions as an adaptor component of the Skp1, Cullin, F-box (SCF) and mediates substrates recruitment to the Cullin-RING E3 ubiquitin ligase (CRL) complex
  • Cyclin E, c-Myc, c-Jun, Notch1, SREBP, mTOR, c-Myb, MCL1, NFκB2, and GATA3 are all known substrates targeted by Fbxw7 for ubiquitin-proteasome system- (UPS-) mediated degradation.

Compare Similar Items

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MilliporeSigma™

ABE1379MI

--


Antigen:
F-box/WD repeat-containing protein 7

Classification:
Polyclonal

Gene Accession No.:
Q969H0

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
FBXW7; FBW7; FBX30; SEL10

Immunogen:
KLH-conjugated linear peptide corresponding to human F-box/WD repeat-containing protein 7.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_060785

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Img

MilliporeSigma

ABE1387MI

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Antigen:
Nuclear factor 1/C

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Applications:
ChIP Assay, Electromobility Shift Assay, Western Blot

Formulation:
Rabbit polyclonal serum containing 0.05% sodium azide.

Gene Symbols:
NFIC; NFI

Immunogen:
Recombinant protein corresponding to full length Human NFIC.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
NP_001231931

Content And Storage:
-20°C in undiluted aliquots for up to 12 months, Avoid Freeze/Thaw Cycles

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MilliporeSigma™

ABE1397MI

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Antigen:
trimethyl STAT3 (Lys180)

Classification:
Polyclonal

Gene Accession No.:
P40763

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Applications:
Immunoprecipitation, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
STAT3; APRF

Immunogen:
KLH-conjugated linear peptide corresponding to the STAT3 K180me3 of human trimethyl STAT3 (Lys180)

Quantity:
100 μL

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_644805

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

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ABE1398MI

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Antigen:
Proline-rich Protein 14

Classification:
Polyclonal

Gene Accession No.:
Q9BWN1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Applications:
Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
PRR14

Immunogen:
KLH-conjugated linear peptide corresponding to human Proline-rich Protein 14.

Quantity:
100 μL

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_076936

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.