ABS1652MI
MilliporeSigma™ anti-GSTA4, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1652MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABS1652MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
GSTA4
Classification
Polyclonal
Formulation
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols
Gsta4
Immunogen
Purified rat liver GST K (YkYk).
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_001100310
Target Species
Mouse, Rat
Form
Serum
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Gene Accession No.
P14942
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This antiserum selectively reacts with Yk from purified rat liver GST K and rat kidney GST J. No reactivity toward Ya, Yc, Yb1, Yb2, Yb3, Yf, or Yn subunits from other forms of purified rat GSTs (Hayes, J.D,, and Mantle, T.J. (1986). Biochem. J. 233(3):779-788).
Content And Storage
−20°C for one year
Related Products
Description
- Specifically detects GSTA4 Clone: in Mouse, Rat samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Glutathione S-transferase alpha-4 (EC:2.5.1.18; UniProt P14942; also known as Glutathione S-transferase A4, Glutathione S-transferase Yk, GST 8-8, GST A4-4, GST K, GST Yk) is encoded by the Gsta4 gene (Gene ID 300850) in rat
- Glutathione S-transferases constitute a family of isozymes that are involved in detoxification by catalyzing the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates
- The GST family can be subdivided into the cytosolic, mitochondrial, and microsomal (a.k.a
- MAPEG) proteins
- Mammalian GSTs exist either as homodimers or heterodimers
- The individual monomers were historically characterized by their quaternary structure and size, Yf (24.5kDa), Yk (25kDa), Ya1 (25.5kDa), Ya2 (25.5kDa), Yn (26.5kDa), Yb1 (27kDa), Yb2 (27kDa) and Yc (28.5kDa)
- The Y designation refers to the Y fraction (as opposed to the X and Z fractions) that were found during purification by Sephadex G75 chromatography
- Two GST superfamilies exist that comprise either cytosolic or membrane-bound proteins
- Evidence suggests that cytosolic GST increases bodily resistance to carcinogens, products of oxidative stress, environmental pollutants and certain anti-cancer drugs
- The cytosolic GSTs are further subdivided into eight classes, namely alpha (GSTA), mu (GSTM), pi (GSTP), sigma (GSTS), theta (GSTT), kappa (GSTK), zeta (GSTZ), and omega (GSTO)
- GSTA4 exists as a homodimer composed of two Yk subunits.
Compare Similar Items
Show Difference
Antigen: GSTA4
Classification: Polyclonal
Formulation: Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols: Gsta4
Immunogen: Purified rat liver GST K (YkYk).
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001100310
Target Species: Mouse, Rat
Form: Serum
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Gene Accession No.: P14942
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antiserum selectively reacts with Yk from purified rat liver GST K and rat kidney GST J. No reactivity toward Ya, Yc, Yb1, Yb2, Yb3, Yf, or Yn subunits from other forms of purified rat GSTs (Hayes, J.D,, and Mantle, T.J. (1986). Biochem. J. 233(3):779-788).
Content And Storage: −20°C for one year
Antigen:
GSTA4
Classification:
Polyclonal
Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols:
Gsta4
Immunogen:
Purified rat liver GST K (YkYk).
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001100310
Target Species:
Mouse, Rat
Form:
Serum
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
P14942
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This antiserum selectively reacts with Yk from purified rat liver GST K and rat kidney GST J. No reactivity toward Ya, Yc, Yb1, Yb2, Yb3, Yf, or Yn subunits from other forms of purified rat GSTs (Hayes, J.D,, and Mantle, T.J. (1986). Biochem. J. 233(3):779-788).
Content And Storage:
−20°C for one year
Antigen: GSTT1
Classification: Polyclonal
Formulation: Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols: GSTT1
Immunogen: His-tagged recombinant full-length human GSTT1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000844
Target Species: Human, Mouse, Rat
Form: Serum
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Gene Accession No.: P30711
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both spliced isoforms reported by UniProt (P30711). Note that not all human samples are positive for GSTT1 expression. It has been estimated that approx. 18% of the Caucasian, and as much as 60% of the Chinese and Korean populations are GSTT1-null (Katoh, T., et al. (1996) Carcinogenesis. 17(9):1855-1859; Lear, J.T., et al. (1996) Carcinogenesis. 17(9):1891-1896;).
Content And Storage: −20°C for one year
Antigen:
GSTT1
Classification:
Polyclonal
Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols:
GSTT1
Immunogen:
His-tagged recombinant full-length human GSTT1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000844
Target Species:
Human, Mouse, Rat
Form:
Serum
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
P30711
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both spliced isoforms reported by UniProt (P30711). Note that not all human samples are positive for GSTT1 expression. It has been estimated that approx. 18% of the Caucasian, and as much as 60% of the Chinese and Korean populations are GSTT1-null (Katoh, T., et al. (1996) Carcinogenesis. 17(9):1855-1859; Lear, J.T., et al. (1996) Carcinogenesis. 17(9):1891-1896;).
Content And Storage:
−20°C for one year
Antigen: PDI
Classification: Polyclonal
Formulation: Purified rabbit polyclonal antibody in PBS with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: Linear peptide corresponding to the N-terminal sequence of arginylated mature human PDI.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000909
Target Species: Human
Form: __
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Gene Accession No.: P07237
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody specifically detected the immunogen peptide, but not the control peptide without arginylation at the N-terminal Asp18 (Cha-Molstad, H., et al. (2015). Nat. Cell Biol. 17(7):917-929).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Antigen:
PDI
Classification:
Polyclonal
Formulation:
Purified rabbit polyclonal antibody in PBS with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
Linear peptide corresponding to the N-terminal sequence of arginylated mature human PDI.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000909
Target Species:
Human
Form:
__
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
P07237
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody specifically detected the immunogen peptide, but not the control peptide without arginylation at the N-terminal Asp18 (Cha-Molstad, H., et al. (2015). Nat. Cell Biol. 17(7):917-929).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Antigen: CHMP3
Classification: Polyclonal
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Symbols: CHMP3;CGI149;NEDF;VPS24;CGI-149
Immunogen: A full-length human recombinant charged multivesicular body protein 3 (CHMP3).
Quantity: 25 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Target Species: Human
Form: Serum
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Charged multivesicular body protein 3 in human cells.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Antigen:
CHMP3
Classification:
Polyclonal
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Symbols:
CHMP3;CGI149;NEDF;VPS24;CGI-149
Immunogen:
A full-length human recombinant charged multivesicular body protein 3 (CHMP3).
Quantity:
25 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Target Species:
Human
Form:
Serum
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Charged multivesicular body protein 3 in human cells.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.