ABE1959

MilliporeSigma™ RAD9A, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABE1959-Each-of-1 In Stock ₹ 38,734.72

ABE1959 - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

RAD9A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rad9a, Rad9

Host Species

Rabbit

Purification Method

Protein A Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This rabbit polyclonal antibody detected nuclear RAD9A immunoreactivity in human and mouse tissue sections.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt..

Applications

Immunohistochemistry (Paraffin)

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q9Z0F6

Immunogen

GST-tagged recombinant full-length mouse RAD9A.

Quantity

100 μg

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

NP_035367

Target Species

Human

Form

Purified

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Description

  • Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2; UniProt Q9Z0F6; also known as DNA repair exonuclease rad9 homolog A, mRAD9, Rad9-like protein) is encoded by the Rad9a (also known as Rad9) gene (Gene ID 19367) in murine species
  • RAD9A is a component of the trimeric PCNA-like 9-1-1 complex (Rad9A, Rad1, and Hus1) and plays an important role in maintaining genomic integrity
  • RAD9A participates in both ATR and ATM signaling pathways-mediated cell cycle checkpoints in mitosis
  • Evidences indicate that RAD9A participates in DNA damage repair by interacting with proteins involved in base excision repair, mismatch repair and homologous recombination repair
  • RAD9A is shown to colocalize with γH2AX following DNA damage induction in an ATM-independent manner, and RAD9A inactivation delays the appearance of ionizing radiation-induced γH2AX foci
  • Rad9a-knockout causes embryonic lethality in mice due to increased apoptotic activity and reduced cellular proliferation, while mice heterozygous for Rad9a are prone to spontaneous and radiation-induced cataractogenesis
  • In addition, conditional knockout in keratinocytes causes enhanced susceptibility to carcinogen-induced skin tumors, while conditional Rad9a deletion in undifferentiated spermatogonia results in drastic effects on meiosis.

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MilliporeSigma™

ABE1959

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Antigen:
RAD9A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rad9a, Rad9

Host Species:
Rabbit

Purification Method:
Protein A Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detected nuclear RAD9A immunoreactivity in human and mouse tissue sections.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt..

Applications:
Immunohistochemistry (Paraffin)

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q9Z0F6

Immunogen:
GST-tagged recombinant full-length mouse RAD9A.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_035367

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

ABE1961MI

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Antigen:
Borealin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody detects Borealin in nocodozole treated HeLa cells.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot, Immunofluorescence, Immunoprecipitation

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
A His-tagged full length human recombinant Borealin.

Quantity:
50 μL

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_060571

Target Species:
Human

Form:
Serum

Img

MilliporeSigma

ABE1971-I-25

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Antigen:
phospho TFEB (Ser142)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody specifically detects Transcription factor EB phosphorylated on Serine 142 in human cells.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 15 amino acids surrounding phosphoserine 142 from the N-terminal half of human Transcription factor EB, isoform 1.

Quantity:
25 μL

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_001161299

Target Species:
Human

Form:
__

Img

MilliporeSigma

ABE1972MI

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Antigen:
Ash2L Antibody

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Specificity was confirmed by decreased target band detection in lysates from Ash2L shRNA-treated C2C12 cells (Rampalli, S., et al. (2007). Nat. Struct. Mol. Biol. 14(12):1150-1156).

Content And Storage:
Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
ChIP Assay, Immunoprecipitation, Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
Recombinant full-length human AshL.

Quantity:
100 μL

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_004665

Target Species:
Human, Mouse

Form:
Serum