ABE1013IMI
MilliporeSigma™ ALKBH5, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1013IMI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABE1013IMI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
ALKBH5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ALKBH5, ABH5, OFOXD1
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with all three spliced isoforms of human ALKBH5 reported by UniProt (Q6P6C2).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q6P6C2
Immunogen
GST-tagged recombinant human ALKBH5 C-terminal fragment.
Quantity
100 μL
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_060228
Target Species
Human
Related Products
Description
- RNA demethylase ALKBH5 (UniProt Q6P6C2; also known as Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5) is encoded by the ALKBH5 (also known as ABH5, OFOXD1) gene (Gene ID 54890) in human
- More than 100 types of postranscriptional RNA modifications are known, among which N6-methyladenosine (m6A) is the most common RNA modification
- m6A modification mainly occurs in the consensus seqeunce motif RRm6ACH (R = A/G and H = A/C/U) located in stop codons, long internal exons as well as 3′ UTR
- RNA methyltransferases and demethylases are responsible for maintaining the level of cellular RNA m6A methylation
- Two Fe2+ and 2-oxoglutarate (2OG) dependent AlkB dioxygenases family members, the fat mass and obesity-associated (FTO) enzyme and ALKBH5, catalyze the oxidative demethylation of abundant m6A residues
- Both FTO and ALKBH5 are localized to nucleus and ALKBH5 gene knockdown is shown to affect cellular mRNA splicing in vitro and result in sterility phenotype in male mice in vivo.
Compare Similar Items
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Antigen: ALKBH5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ALKBH5, ABH5, OFOXD1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all three spliced isoforms of human ALKBH5 reported by UniProt (Q6P6C2).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q6P6C2
Immunogen: GST-tagged recombinant human ALKBH5 C-terminal fragment.
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_060228
Target Species: Human
Antigen:
ALKBH5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ALKBH5, ABH5, OFOXD1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all three spliced isoforms of human ALKBH5 reported by UniProt (Q6P6C2).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q6P6C2
Immunogen:
GST-tagged recombinant human ALKBH5 C-terminal fragment.
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_060228
Target Species:
Human
Antigen: monomethyl-Histone H3 (Lys79)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Applications: ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
Concentration: __
Formulation: Rabbit polyclonal in buffer containing serum with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: Linear peptide corresponding to human Histone H3 (Lys79).
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_003484
Target Species: Human, Yeast
Antigen:
monomethyl-Histone H3 (Lys79)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Applications:
ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal in buffer containing serum with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
Linear peptide corresponding to human Histone H3 (Lys79).
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_003484
Target Species:
Human, Yeast
Antigen: monomethyl-Histone H3 (Lys9)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunocytochemistry, Inhibition Assays, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated branched peptide corresponding to human Histone H3 methylated at Lys9.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_003484.1
Target Species: Human
Antigen:
monomethyl-Histone H3 (Lys9)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunocytochemistry, Inhibition Assays, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated branched peptide corresponding to human Histone H3 methylated at Lys9.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_003484.1
Target Species:
Human
Antigen: monomethyl-Histone H3 (Lys9)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Dot Blot, Immunocytochemistry, Inhibition Assays, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated branched peptide corresponding to human Histone H3 methylated at Lys9.
Quantity: 10 μg
Research Discipline: __
Gene ID (Entrez): NP_003484.1
Target Species: Human
Antigen:
monomethyl-Histone H3 (Lys9)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Dot Blot, Immunocytochemistry, Inhibition Assays, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated branched peptide corresponding to human Histone H3 methylated at Lys9.
Quantity:
10 μg
Research Discipline:
__
Gene ID (Entrez):
NP_003484.1
Target Species:
Human