ABT1488MI
MilliporeSigma™ MCAM/CD146, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT1488MI-Each-of-1 | In Stock | ₹ 41,643.76 |
ABT1488MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,643.76
GST (18%): ₹ 7,495.877
Total Price: ₹ 49,139.637
Antigen
MCAM/CD146
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MCAM, MUC18
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with both spliced isoforms of human MCAM/CD146 reported by UniProt (P43121).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunoprecipitation, Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P43121
Immunogen
KLH-conjugated linear peptide corresponding to a sequence from the third C2-type Ig-like domain of human MCAM/CD146.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_006491
Target Species
Human
Related Products
Description
- Cell surface glycoprotein MUC18 (UniProt P43121; also known as CD146, Cell surface glycoprotein P1H12, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, Melanoma cell adhesion molecule, S-endo 1 endothelial-associated antigen) is encoded by the MCAM (also known as MUC18) gene (Gene ID 4162) in human
- MUC18/CD146 is an 113kDa transmembrane immunoglobulin superfamily glycoprotein mainly expressed on endothelial cells and smooth muscle cells where it functions as a cell-to-cell adhesion molecule, while little or no expression is found among epithelial cells and leukocytes (e.g
- macrophages and neutrophils)
- Originally characterized as a protein overexpressed in malignant melanoma cells and adopted the name MCAM (melanoma cell adhesion molecule), MUC18/CD146 up-regulation is also reported in airway epithelial cells of patients with asthma and chronic obstructive pulmonary disease (COPD)
- Cellular overexpression and knockdown studies indicate that MUC18/CD146 plays a pro-inflammatory role in response to stimulation with various TLR agonists
- MUC18/CD146 is produced with a signal peptide (a.a
- 1-23) sequence, the removal of which yields the mature protein with a large extracellular region (a.a
- 24-559), followed by a transmembrane domain (a.a
- 560-583) and a cytoplasmic domain (a.a
- 584-646)
- The extracellular region contains two V-type (a.a
- 24-129 and 139-242) and three C2-type (a.a
- 244-330, 335-424, 430-510) Ig-like domains.
Compare Similar Items
Show Difference
Antigen: MCAM/CD146
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCAM, MUC18
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both spliced isoforms of human MCAM/CD146 reported by UniProt (P43121).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunoprecipitation, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P43121
Immunogen: KLH-conjugated linear peptide corresponding to a sequence from the third C2-type Ig-like domain of human MCAM/CD146.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_006491
Target Species: Human
Antigen:
MCAM/CD146
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCAM, MUC18
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both spliced isoforms of human MCAM/CD146 reported by UniProt (P43121).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunoprecipitation, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P43121
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the third C2-type Ig-like domain of human MCAM/CD146.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_006491
Target Species:
Human
Antigen: Claudin-11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_005593
Target Species: Human
Antigen:
Claudin-11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_005593
Target Species:
Human
Antigen: Cofilin-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CFL, CFL1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P23528
Immunogen: KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_005498
Target Species: Human
Antigen:
Cofilin-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CFL, CFL1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P23528
Immunogen:
KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_005498
Target Species:
Human
Antigen: Cofilin-1
Classification: Polyclonal
Conjugate: Alexa Fluor 488
Gene: CFL, CFL1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This Alexa Fluor™ 488-conjugated polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunocytochemistry
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.: P23528
Immunogen: KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_005498
Target Species: Human
Antigen:
Cofilin-1
Classification:
Polyclonal
Conjugate:
Alexa Fluor 488
Gene:
CFL, CFL1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This Alexa Fluor™ 488-conjugated polyclonal antibody targets cofilin-1 N-terminal end sequence conserved among bovine, human, mouse, porcine, and rat species.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunocytochemistry
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.
Gene Accession No.:
P23528
Immunogen:
KLH-conjugated linear peptide corresponding to the N-termnal end sequence of human cofilin-1.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_005498
Target Species:
Human