ABC943MI
MilliporeSigma™ MATE2/SLC47A2, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABC943MI-Each-of-1 | In Stock | ₹ 41,307.51 |
ABC943MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
MATE2/SLC47A2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLC47A2, MATE2
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
The immunogen sequence is present only in the canonical form (UniProt Q86VL8-1) of human SLC47A2, but not any of the other five spliced isoforms reported by Uniprot (Q86VL8-2 through Q86VL8-6).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q86VL8
Immunogen
KLH-conjugated linear peptide corresponding to a sequence from the third cytoplasmic domain of human MATE2/SLC47A2.
Quantity
100 μg
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_690872
Target Species
Human
Related Products
Description
- Multidrug and toxin extrusion protein 2 (UniProt Q86VL8; also known as hMATE-2, Kidney-specific H(+)/organic cation antiporter, MATE-2, Solute carrier family 47 member 2) is encoded by the SLC47A2 (also known as MATE2) gene (Gene ID 146802) in human
- Multidrug and toxin extrusion (MATE) proteins are transporters mediating the efflux of organic cations from cells
- Driven by oppositely directed proton gradient, MATEs are considered secondary active transporters
- MATEs are located at the apical membrane of proximal tubular cells and work in concert with the basal organic cation transporters (OCTs) in the elimination of cationic drugs from the kidney
- Human SLC47A2 gene produces two functional isoforms, the 602-a.a
- canonical MATE2 (NP_690872.2; UniProt Q86VL8-1) and the shorter spliced isoform 566-a.a
- MATE2-K (NP_001093116.1; UniProt Q86VL8-3) lacking a.a
- 178-213 of MATE2 due to a partial deletion of exon 7-coding sequence
- MATE2 and MATE2-K are preferentially localized in the kidney, while MATE2 is also detected in the placenta
- MATE2 contains 13 transmembrane (a.a
- 34-54, 67-87, 120-140, 154-174, 220-240, 249-269, 290-309, 328-348, 369-389, 403-423, 443-463, 467-487, 488-578) helices (TMHs), having its N-terminal end (a.a
- 1-33) at the cytoplasmic side and its C-terminus (a.a
- 600-602) at the extracellular side
- The first twelve TMHs are required for proper transport function while the thirteenth TMH is likely needed for protein turnover.
Compare Similar Items
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Antigen: MATE2/SLC47A2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC47A2, MATE2
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The immunogen sequence is present only in the canonical form (UniProt Q86VL8-1) of human SLC47A2, but not any of the other five spliced isoforms reported by Uniprot (Q86VL8-2 through Q86VL8-6).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q86VL8
Immunogen: KLH-conjugated linear peptide corresponding to a sequence from the third cytoplasmic domain of human MATE2/SLC47A2.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_690872
Target Species: Human
Antigen:
MATE2/SLC47A2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC47A2, MATE2
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The immunogen sequence is present only in the canonical form (UniProt Q86VL8-1) of human SLC47A2, but not any of the other five spliced isoforms reported by Uniprot (Q86VL8-2 through Q86VL8-6).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q86VL8
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the third cytoplasmic domain of human MATE2/SLC47A2.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_690872
Target Species:
Human
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Antigen: PSAT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSAT1, NLS2, PSA, PSATD
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The immunogen sequence is 100% conserved in murine PSAT1 (UniProt Q99K85) and present in both spliced isoforms of human PSAT1 (Uniprot Q9Y617).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q9Y617
Immunogen: KLH-conjugated linear peptide corresponding to a sequence within the region between the two pyridoxal phosphate-binding domains of human PSAT1.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_478059
Target Species: Human
Antigen:
PSAT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSAT1, NLS2, PSA, PSATD
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The immunogen sequence is 100% conserved in murine PSAT1 (UniProt Q99K85) and present in both spliced isoforms of human PSAT1 (Uniprot Q9Y617).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q9Y617
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence within the region between the two pyridoxal phosphate-binding domains of human PSAT1.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_478059
Target Species:
Human
Antigen: Praf2 (JM4)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum containing with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human Praf2 (JM4).
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_009144
Target Species: Human, Mouse, Rat
Antigen:
Praf2 (JM4)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum containing with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human Praf2 (JM4).
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_009144
Target Species:
Human, Mouse, Rat