ABS209925UG

STRN3, Rabbit anti-Mouse, Human, Polyclonal, Millipore Sigma™

Manufacturer: MilliporeSigma

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Pack Size SKU Availability Price
Each of 1 ABS209925UG-Each-of-1 In Stock ₹ 15,999.72

ABS209925UG - Each of 1

₹ 15,999.72

In Stock

Quantity

1

Base Price: ₹ 15,999.72

GST (18%): ₹ 2,879.95

Total Price: ₹ 18,879.67

Antigen

STRN3

Classification

Polyclonal

Dilution

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected STRN3 in HeLa cells.

Gene Alias

Cell cycle autoantigen SG2NA;S/G2 antigen

Host Species

Rabbit

Molecular Weight of Antigen

∽87 kDa observed; 87.21 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity

25 μg

Research Discipline

Signaling

Test Specificity

This rabbit polyclonal antibody detect Striatin-3 in human and murine cells. It targets an epitope within 17 amino acids from the N-terminal half.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

STRN3;GS2NA;SG2NA

Immunogen

KLH-conjugated linear peptide corresponding to 17 amino acids from the N-terminal half of human Striatin-3. The immunogen sequence is conserved in both alpha and beta isoforms.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse, Human

Form

Purified

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Description

  • Anti-STRN3, Cat
  • No
  • ABS2099, is a rabbit polyclonal antibody that detects Striatin-3 and has been tested for use in Immunocytochemistry and Western Blotting
  • Striatin-3 (UniProt: Q13033; also known as Cell cycle autoantigen SG2NA, S/G2 antigen) is encoded by the STRN3 (also known as GS2NA, SG2NA) gene (Gene ID: 29966) in human
  • Striatin-3 is a calmodulin-binding protein that bonds calmodulin a calcium dependent manner and may function as scaffolding or signaling protein
  • Two isoforms of Striatin-3 have been reported that are produced by alternative splicing
  • Its calmoduln-binding region is located within amino acids 166-183
  • It also contains a caveolin-binding region (aa 71-79), six WD repeats, and a coiled coil region (aa 77-136)
  • The coiled coil domain and the PP2A subunit can form a stable core complex with a 2:2 stoichiometry
  • The coiled coil domain of striatin-3 is a novel type of PP2A regulatory subunit that functions as a scaffold for the assembly of the STRIPAK complex
  • PP2A and certain kinases, such as germinal central kinase III (GCKIII) interact with striatin to form striatin-interacting phosphatase and kinase (STRIPAK) complex that are known to regulate multiple cellular events
  • Wild-type striatin-3 is shown to strongly suppress apoptosis in Jurkat cells induced by the GCKIII kinase MST3
  • However, mutant forms of striatin-3 fail to exhibit this effect
  • (Ref.: Lu, Q., et al
  • (2004)
  • Proc
  • Natl
  • Acad
  • Sci
  • USA 101(49); 17126-17131; Chen, C., et al
  • (2014)
  • J
  • Biol
  • Chem
  • 289(14); 9651-61).

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Antigen:
STRN3

Classification:
Polyclonal

Dilution:
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected STRN3 in HeLa cells.

Gene Alias:
Cell cycle autoantigen SG2NA;S/G2 antigen

Host Species:
Rabbit

Molecular Weight of Antigen:
∽87 kDa observed; 87.21 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity:
25 μg

Research Discipline:
Signaling

Test Specificity:
This rabbit polyclonal antibody detect Striatin-3 in human and murine cells. It targets an epitope within 17 amino acids from the N-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
STRN3;GS2NA;SG2NA

Immunogen:
KLH-conjugated linear peptide corresponding to 17 amino acids from the N-terminal half of human Striatin-3. The immunogen sequence is conserved in both alpha and beta isoforms.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human

Form:
Purified

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ABS2103

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Antigen:
BiP (GRP78), arginylated (Nt-Glu19)

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Research Discipline:
Signaling

Test Specificity:
This rabbit polyclonal antibody specifically detected the immunogen peptide, but not the control peptide without arginylation at the N-terminal Glu19 (Cha-Molstad, H., et al. (2015). Nat. Cell Biol. 17(7):917-929).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
__

Applications:
ELISA, Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing PBS with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
Linear peptide corresponding to the N-terminal sequence of arginylated mature human BiP (GRP78).

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
__

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ABS210725UL

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Antigen:
phospho-CaMKII beta (Ser331)

Classification:
Polyclonal

Dilution:
Western Blotting Analysis: A representative lot detected phospho-CaMKII beta (Ser331) in HEK293T cells transfected with CaMKII WT or mutants (Kim, K., et. al. (2015). Neuron. 87(4):813-26).Immunocytochemistry Analysis: A representative lot detected phospho-CaMKII beta (Ser331) in dissociated hippocampal neurons (Kim, K., et. al. (2015). Neuron. 87(4):813-26).

Gene Alias:
Calcium/calmodulin-dependent protein kinase type II subunit beta;EC: 2.7.11.17;CaM kinase II subunit beta;CaMK-II beta

Host Species:
Rabbit

Molecular Weight of Antigen:
∽60 kDa observed; 60.40 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity:
25 μL

Research Discipline:
Neuroscience

Test Specificity:
This rabbit polyclonal antibody detects beta subunit of CaM Kinase II when phosphorylated on Ser331.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
Camk2b

Immunogen:
A linear peptide corresponding to 10 amino acids surrounding phopho serine 331 of rat CaM Kinase II beta.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
__

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ABS2113

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Classification:
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Content And Storage:
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Isotype:
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Applications:
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Conjugate:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
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Target Species:
__

Form:
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