APPA6824

LXR alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 APPA6824-Each-of-1 In Stock ₹ 44,362.86

APPA6824 - Each of 1

₹ 44,362.86

In Stock

Quantity

1

Base Price: ₹ 44,362.86

GST (18%): ₹ 7,985.315

Total Price: ₹ 52,348.175

Antigen

LXR alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NR1H3

Gene Alias

AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10062, 22259, 397553

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Western Blot

Concentration

1.04 mg/mL

Formulation

tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.

Q13133, Q9Z0Y9

Gene Symbols

NR1H3

Immunogen

A synthetic peptide made to an internal portion of the human LXR protein sequence (between residues 50-150).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Porcine

Product Type

Antibody

Isotype

IgG

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Description

  • The target sequence has 92% sequence homology with rat and mouse, and 90% sequence homology with chicken
  • Suggested positive control: human liver lysate, human liver protein
  • NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activation activity
  • Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES
  • LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides
  • NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8
  • It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.

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Thermo Scientific

APPA6824

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Antigen:
LXR alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10062, 22259, 397553

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Concentration:
1.04 mg/mL

Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.:
Q13133, Q9Z0Y9

Gene Symbols:
NR1H3

Immunogen:
A synthetic peptide made to an internal portion of the human LXR protein sequence (between residues 50-150).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

APPA6826

--


Antigen:
CENPF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CENPF

Gene Alias:
6530404A22Rik; AH antigen; AI325968; cell-cycle-dependent 350K nuclear protein; CENF; CENPF; CENP-F; CENP-F kinetochore protein; centromere autoantigen F; centromere protein F; centromere protein F, (mitosin); centromere protein F, 350/400ka (mitosin); centromere protein F, 350/400kDa (mitosin); CILD31; hcp-1; im:7140452; im:7144238; im:7154719; im:7156761; kinetochore protein CENPF; Lek1; leucine, glutamic acid, lysine family 1 protein; mitosin; PRO1779; RP11-262H5.1; si:ch211-152h14.2; STROMS

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100050180, 1063, 108000, 533089

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P49454

Gene Symbols:
CENPF

Immunogen:
A bacterial fusion protein from the C-terminus of CENP-F.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Equine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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APPA6828

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Antigen:
SPAG5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPAG5

Gene Alias:
AI874642; Astrin; D11Bhm180e; Deepest; hMAP126; MAP126; Mastrin; microtubule-associated protein; mitotic spindle associated protein p126; mitotic spindle coiled-coil related protein; mitotic spindle-associated protein p126; S17; Spag5; sperm associated antigen 5; sperm-associated antigen 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10615

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q96R06

Gene Symbols:
SPAG5

Immunogen:
Full length recombinant protein to MAP126

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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APPA6830

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Antigen:
POT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POT1

Gene Alias:
1500031H18Rik; AI505244; AI851169; CMM10; DKFZp586D211; Dolichyl-phosphate-mannose--protein mannosyltransferase 1; GLM9; HPOT1; mPot1; Pomt1; POT 1; POT1; POT-1; Pot1a; POT1-like telomere end-binding protein; protection of telomeres 1; protection of telomeres 1 homolog; protection of telomeres 1A; protection of telomeres protein 1; protein O-mannosyltransferase 1; Protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25913

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Concentration:
1.0 mg/mL

Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.:
Q9NUX5

Gene Symbols:
POT1

Immunogen:
A synthetic peptide made to an internal portion of the human POT1 protein sequence (between residues 200-300).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG