BDB554069

p27 (Kip1) Mouse, Unlabeled, Clone: G173-524, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554069-Each-of-1 In Stock ₹ 30,929.94

BDB554069 - Each of 1

₹ 30,929.94

In Stock

Quantity

1

Base Price: ₹ 30,929.94

GST (18%): ₹ 5,567.389

Total Price: ₹ 36,497.329

Antigen

p27 (Kip1)

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Mouse p27 [Kip1] (full-length) Recombinant Protein

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human, Mouse

Isotype

IgG1

Applications

Western Blot

Clone

G173-524

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes
  • Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle
  • These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small proteins that bind to cyclins, cdks, or cyclin-cdk complexes
  • These include p15, p16, p18, p19, p21 and p27 [Kip1]
  • p27 [Kip1] has been shown to inhibit the activity of multiple cyclin-cdk complexes, including cyclin D-cdk4, cyclin E-cdk2 and cyclin A-cdk2
  • p27 [Kip1] is a 27kDa protein which shares N-terminal sequence homology with p21, and like p21, p27 [Kip1] contains a nuclear localization signal in its C-terminal region
  • IL-2 activation of T cells has been reported to lead to a decrease in p27 [Kip1] and entry into S phase
  • Removal of IL-2 from T cell cultures results in increased levels of p27 [Kip1] and cell quiescence
  • Host Species: Mouse Clone: G173-524 Isotype: IgG1 Species Reactivity: Mouse Immunogen: Mouse p27 [Kip1] (full-length) Recombinant Protein Formula Weight [Chemical]: 27kDa Bioimaging, Immunoprecipitation, Western Blotting

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Antigen:
p27 (Kip1)

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse p27 [Kip1] (full-length) Recombinant Protein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
G173-524

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
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Concentration:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

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Quantity:
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Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
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Conjugate:
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Purification Method:
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RUO

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Primary

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Store undiluted at 4°C

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Target Species:
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Host Species:
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Primary or Secondary:
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Content And Storage:
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