BDB554164
Underphosphorylated Retinoblastoma Mouse anti-Human, Unlabeled, Clone: G99-549, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554164-Each-of-1 | In Stock | ₹ 29,261.52 |
BDB554164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,261.52
GST (18%): ₹ 5,267.074
Total Price: ₹ 34,528.594
Antigen
Underphosphorylated Retinoblastoma
Classification
Monoclonal
Concentration
0.5mg/mL
Description
RB (a.a. 514-610)
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Immunoprecipitation
Clone
G99-549
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Recombinant full-length human Rb
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG1
Related Products
Description
- The retinoblastoma gene encodes a nuclear phosphoprotein (Rb or p110Rb) which is expressed in most normal cells of vertebrates and acts as a tumor suppressor gene product
- An underphosphorylated form of Rb is mainly found in resting or fully differentiated cells, whereas the hyperphosphorylated form is present in proliferating cells
- Only the underphosphorylated form of Rb binds specifically to viral oncogenes such as SV40 large T, adenoviral EIA and HPV-E7
- This interaction may partially contribute to the transforming activity of these viral oncoproteins
- Rb also interacts with several cyclins including A, D, and E as well as the transcriptional activator E2F
- The importance of these interactions for the biological function of Rb is still being elucidated
- G99-549 recognizes only the fast migrating, underphosphorylated form of Rb protein
- G99-549 cross-reacts with mouse underphosphorylated Rb
- The epitope has been mapped to amino acids 514-610 (box A) of human Rb
- Recombinant full-length human Rb was produced in the baculovirus expression vector system (BEVS), purified and used as immunogen
- Host Species: Mouse Clone: G99-549 Isotype: IgG1 Species Reactivity: Human Immunogen: Recombinant full-length human Rb Formula Weight [Chemical]: 105kDa Immunoprecipitation, Western Blotting
Compare Similar Items
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Antigen: Underphosphorylated Retinoblastoma
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: RB (a.a. 514-610)
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Immunoprecipitation
Clone: G99-549
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant full-length human Rb
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1
Antigen:
Underphosphorylated Retinoblastoma
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
RB (a.a. 514-610)
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Immunoprecipitation
Clone:
G99-549
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant full-length human Rb
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1
Antigen: p53
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: PAB 240
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human p53 aa. 14-289
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Bovine, Chicken, Hamster, Human, Monkey, Mouse, Rat
Isotype: IgG1
Antigen:
p53
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
PAB 240
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human p53 aa. 14-289
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Bovine, Chicken, Hamster, Human, Monkey, Mouse, Rat
Isotype:
IgG1
Antigen: p53
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: PAB 240
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human p53 aa. 14-289
Quantity: 0.25 mg
Research Discipline: Cell Biology
Target Species: Bovine, Chicken, Hamster, Human, Monkey, Mouse, Rat
Isotype: IgG1
Antigen:
p53
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
PAB 240
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human p53 aa. 14-289
Quantity:
0.25 mg
Research Discipline:
Cell Biology
Target Species:
Bovine, Chicken, Hamster, Human, Monkey, Mouse, Rat
Isotype:
IgG1
Antigen: p53
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: PAB 1801
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant fusion protein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Antigen:
p53
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
PAB 1801
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant fusion protein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1