BDB554254

CD95 Hamster anti-Mouse, NA/LE, Unlabeled, Clone: JO2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554254-Each-of-1 In Stock ₹ 37,475.28

BDB554254 - Each of 1

₹ 37,475.28

In Stock

Quantity

1

Base Price: ₹ 37,475.28

GST (18%): ₹ 6,745.55

Total Price: ₹ 44,220.83

Antigen

CD95

Classification

Monoclonal

Concentration

1.0mg/mL

Description

Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

JO2

Conjugate

Unconjugated

Formulation

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

WR19L mouse lymphoma cells transformed with recombinant mouse Fas

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2

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Description

  • Fas antigen, CD95, is a 45kDa cell-surface protein which can mediate apoptosis
  • It belongs to the TNF (tumor necrosis factor)/NGF receptor family
  • Expression of Fas has been described in the thymus, liver, heart, lung and ovary
  • Fas plays an important role in the apoptotic process that takes place during development
  • Monoclonal antibodies recognizing Fas such as Jo2 have cytolytic activity on cells expressing Fas
  • The cell death stimulated by Fas antibodies is characteristic of apoptosis and suggests that the lethal effects are a result of interaction of antibody with a functional Fas antigen as opposed to complement-mediated lysis
  • The Jo2 antibody recognizes mouse Fas
  • The Jo2 antibody shows cytolytic activity against cell lines expressing mouse Fas by inducing apoptosis
  • Intraperitoneal injections of Jo2 mAb have been shown to kill mice and induce apoptotic hepatocyte death
  • Jo2 mAb immunoprecipitates mouse Fas as a 45kDa band from W4 cells
  • W4 cells are WR19L mouse lymphoma cells transformed with mouse Fas
  • The difference between the observed MW of Fas and that deduced from its amino acid sequence (Mr 34,971) may be due to glycosylation.

Compare Similar Items

Show Difference

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BD Biosciences

BDB554254

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Antigen:
CD95

Classification:
Monoclonal

Concentration:
1.0mg/mL

Description:
Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
JO2

Conjugate:
Unconjugated

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
WR19L mouse lymphoma cells transformed with recombinant mouse Fas

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2

Img

BD Biosciences

BDB554256

--


Antigen:
CD95

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
JO2

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
WR19L mouse lymphoma cells transformed with recombinant mouse Fas

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2

Img

Fischer Scientific

BDB554257

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Antigen:
CD95

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Apo-1; Apt1; Fas; FASLG receptor; lpr; TNFR6; Tnfrsf6; TNR6

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
JO2

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
WR19L mouse lymphoma cells transformed with recombinant mouse Fas

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2

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BD Biosciences

BDB554263

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Antigen:
TFE3

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Western Blot

Clone:
G138-312

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
TFE3-L Protein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG1