BDB560306

Oct3/4 Mouse, Alexa Fluor 555, Clone: 40/OCT-3, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560306-Each-of-1 In Stock ₹ 44,148.96

BDB560306 - Each of 1

₹ 44,148.96

In Stock

Quantity

1

Base Price: ₹ 44,148.96

GST (18%): ₹ 7,946.813

Total Price: ₹ 52,095.773

Antigen

OCT3/4

Classification

Monoclonal

Conjugate

Alexa Fluor 555

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

Mouse Oct3 aa. 252-372 Recombinant Protein

Quantity

100 Tests

Research Discipline

Cell Biology

Target Species

Human, Mouse

Isotype

IgG1 κ

Applications

In vitro Assay

Clone

40/OCT-3

Description

Oct3, OTF3, Oct4, OTF4, POU5F1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Development of a multicellular organism from a single fertilized cell is regulated by the coordinated activity of DNA transcription factors
  • Oct3/4, a member of the POU family of transcription factors, functions in pluripotent cells of early embryonic stem cell (ES) lines and embryonal carcinomas (EC)
  • Other members of the POU family include Oct1, Oct2, Pit-1, and unc-86
  • The POU domain, a 150-amino acid region that determines binding specificity, is conserved among these proteins and consists of 3 subdomains: POU-specific A and B subdomains and a homeobox-like subdomain
  • Oct3/4 is expressed in undifferentiated cells, but is lost as cells are induced to differentiate
  • Oct3/4 is not expressed in adult tissues
  • The interaction of Oct3/4 with SOX2, another embryonic transcription factor, produces an active complex that regulates expression of genes such as Nanog, UTF1, and FGF4
  • Although Oct3/4 is specifically phosphorylated on serine residues, this modification is not required for DNA binding, but may affect its transactivation potential
  • Thus, Oct3/4 is a transcription factor that plays an important role in determining early steps of embryogenesis and differentiation
  • Host Species: Mouse Clone: 40 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Mouse Oct3 aa
  • 252-372 Recombinant Protein Bioimaging

Compare Similar Items

Show Difference

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BD Biosciences

BDB560306

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Antigen:
OCT3/4

Classification:
Monoclonal

Conjugate:
Alexa Fluor 555

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Mouse Oct3 aa. 252-372 Recombinant Protein

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Applications:
In vitro Assay

Clone:
40/OCT-3

Description:
Oct3, OTF3, Oct4, OTF4, POU5F1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
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Quantity:
100 Tests

Research Discipline:
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Target Species:
Human, Mouse

Isotype:
IgG3 κ

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Stage-Specific Embryonic Antigen-4

Host Species:
Mouse

Purification Method:
Affinity Purified

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Quantity:
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Research Discipline:
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Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
47

Description:
Signal transducer and activator of transcription 5; MGF; MPF

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
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Conjugate:
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Formulation:
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Immunogen:
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Target Species:
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