BDB558566

PLC-γ Mouse anti-Human, Alexa Fluor 488, Clone: 10/PLCGAMMA, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558566-Each-of-1 In Stock ₹ 25,154.64

BDB558566 - Each of 1

₹ 25,154.64

In Stock

Quantity

1

Base Price: ₹ 25,154.64

GST (18%): ₹ 4,527.835

Total Price: ₹ 29,682.475

Antigen

PLC-γ

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

10/PLCGAMMA

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Cow PLCγ1 N-terminal region Peptide

Quantity

50 Tests

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG1

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Description

  • Description The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol
  • The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C
  • Within the PLC family, PLCγ is the only member that contains SH2 and SH3 domains
  • These domains enable it to interact with receptor tyrosine kinases and become enzymatically activated via phosphorylation
  • It exists as two isoforms: 1) PLCγ1, which is ubiquitously expressed, and 2) PLCγ2, found primarily in the lymphoid system
  • PLCγ is essential for growth factor-induced cell motility and mitogenesis
  • PLCγ1 null mice exhibit retarded embryonic growth and lethality in midgestation
  • Overexpression of PLCγ is evident in several forms of cancer, and it has been identified as a key mediator of PDGF-dependent cellular transformation
  • Thus regulation of PLCγ activity by growth factors is involved in cell growth and transformation
  • The 10/PLCgamma monoclonal antibody recognizes PLCγ1, regardless of phosphorylation status
  • It does not cross-react with PLCγ2
  • Intracellular Staining

Compare Similar Items

Show Difference

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BD Biosciences

BDB558566

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Antigen:
PLC-γ

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
10/PLCGAMMA

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Cow PLCγ1 N-terminal region Peptide

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG1

Img

Fischer Scientific

BDB558569

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Antigen:
__

Classification:
__

Conjugate:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Content And Storage:
In aqueous buffered solution containing BSA™ 0.09% sodium azide at 4°C

Applications:
__

Clone:
__

Formulation:
__

Immunogen:
__

Quantity:
5 mL

Research Discipline:
__

Target Species:
__

Isotype:
__

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BD Biosciences

BDB558570

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Antigen:
HLA-A2

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
BB7.2

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2b κ

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BD Biosciences

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Antigen:
Leukemia Inhibitory Factor

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1F10

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Recombinant vaccinia virus

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ