BDB558129
Btk (pY551) & Itk (pY511) Mouse anti-Human, PE, Clone: 24A/BTK (Y551), BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558129-Each-of-1 | In Stock | ₹ 27,678.66 |
BDB558129 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,678.66
GST (18%): ₹ 4,982.159
Total Price: ₹ 32,660.819
Antigen
Btk (pY551) & Itk (pY511)
Classification
Monoclonal
Conjugate
PE
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
24A/BTK (Y551)
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Btk Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- B ruton's t yrosine k inase (Btk) is a nonreceptor tyrosine kinase whose function is critical for proper B cell development and signaling
- The activity of Btk is regulated by Src mediated phosphorylation of the kinase domain at tyrosine 551 (Y551)
- This event induces Btk kinase activity and subsequent autophosphorylation at Y223
- Phosphorylated Btk then associates with the cell membrane via the interaction of the PH domain with phosphatidylinositol 3, 4, 5-triphosphate
- γ1 (PLC γ1), a key regulator of calcium mobilization and extracellular signal-regulated kinase (ERK) activation
- Itk is regulated by an activating transphosphorylation event in which Y511 in the kinase domain is phosphorylated by Lck
- The 24a/BTK (Y551) monoclonal antibody recognizes the Y551-phosphorylated form of human Btk and the Y511 phosphorylated form of human Itk.
Compare Similar Items
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Antigen: Btk (pY551) & Itk (pY511)
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 24A/BTK (Y551)
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Btk Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
Btk (pY551) & Itk (pY511)
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
24A/BTK (Y551)
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Btk Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: __
Classification: __
Conjugate: Biotin
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: __
Applications: __
Clone: __
Formulation: __
Immunogen: __
Quantity: __
Research Discipline: __
Target Species: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
Biotin
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Content And Storage:
__
Applications:
__
Clone:
__
Formulation:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Target Species:
__
Isotype:
__
Antigen: Btk (pY551) & Itk (pY511)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 24A/BTK (Y551)
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Btk Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
Btk (pY551) & Itk (pY511)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
24A/BTK (Y551)
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Btk Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Stat4 (pY693)
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 38/P-STAT4
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Stat4 (pY693)
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen:
Stat4 (pY693)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
38/P-STAT4
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Stat4 (pY693)
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ