BDB565772
CD274, NA/LE Rat anti-Mouse, Unlabeled, Clone: MIH5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB565772-Each-of-1 | In Stock | ₹ 34,566.24 |
BDB565772 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,566.24
GST (18%): ₹ 6,221.923
Total Price: ₹ 40,788.163
Antigen
CD274, NA/LE
Clone
MIH5
Conjugate
Unconjugated
Gene Alias
B7-H1, PD-L1, PD1L1, Programmed death ligand 1
Immunogen
DBA/2 mouse lymphoma L5178Y transfected with Pdcd1lg1 cDNA
Quantity
500 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C.
Classification
Monoclonal
Concentration
1.0mg/mL
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a λ
Related Products
Description
- The MIH5 monoclonal antibody specifically binds to CD274, also known as B7-H1 or PDL1, a 43-kDa glycoprotein encoded by the Pdcd1lg1 /gene of the B7 family of the Ig superfamily
- Pdcd1lg1 /mRNA is expressed in more tissues than other members of the B7 family; transcripts are found in lymphoid tissues and many, but not all, non-lymphoid tissues
- The protein has been detected at low levels on resting peripheral T and B lymphocytes, macrophages, and dendritic cells
- B7-H1 mRNA and protein expression are upregulated upon activation of T and B cells, macrophages, dendritic cells, and epidermal keratinocytes by a variety of stimulatory factors
- B7-H1's receptor, PD-1, contains an ITIM ( I /mmunoreceptor T /yrosine-based I /nhibitory M /otif) on its intracytoplasmic region and is expressed on activated B and T lymphocytes, suggesting that B7-H1-PD-1 interaction may be involved in the negative regulation of immune responses
- The second PD-1 ligand, B7-DC (PD-L2), is also a member of the B7 family of the Ig superfamily
- Furthermore, B7-H1 may participate in positive immunoregulation, or costimulation of T cells, through an additional receptor, which is not PD-1 and distinct from the alternate receptor for B7-DC
- The MIH5 antibody blocks the binding of PD-1-Ig to B7-H1 transfectants
- NA/LE
Compare Similar Items
Show Difference
Antigen: CD274, NA/LE
Clone: MIH5
Conjugate: Unconjugated
Gene Alias: B7-H1, PD-L1, PD1L1, Programmed death ligand 1
Immunogen: DBA/2 mouse lymphoma L5178Y transfected with Pdcd1lg1 cDNA
Quantity: 500 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C.
Classification: Monoclonal
Concentration: 1.0mg/mL
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a λ
Antigen:
CD274, NA/LE
Clone:
MIH5
Conjugate:
Unconjugated
Gene Alias:
B7-H1, PD-L1, PD1L1, Programmed death ligand 1
Immunogen:
DBA/2 mouse lymphoma L5178Y transfected with Pdcd1lg1 cDNA
Quantity:
500 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C.
Classification:
Monoclonal
Concentration:
1.0mg/mL
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a λ
Antigen: LAG-3 (CD223)
Clone: T47-530
Conjugate: APC-R700
Gene Alias: LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen: Human LAG-3 Recombinant Protein
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
LAG-3 (CD223)
Clone:
T47-530
Conjugate:
APC-R700
Gene Alias:
LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen:
Human LAG-3 Recombinant Protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: LAG-3 (CD223)
Clone: T47-530
Conjugate: APC-R700
Gene Alias: LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen: Human LAG-3 Recombinant Protein
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
LAG-3 (CD223)
Clone:
T47-530
Conjugate:
APC-R700
Gene Alias:
LAG3, CD223, FDC, Lymphocyte activation gene 3 protein, Protein FDC
Immunogen:
Human LAG-3 Recombinant Protein
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Cβ1 TCR
Clone: JOVI.1
Conjugate: PE
Gene Alias: __
Immunogen: __
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Refrigerate (2 to 8°C)
Classification: Monoclonal
Concentration: __
Formulation: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
Cβ1 TCR
Clone:
JOVI.1
Conjugate:
PE
Gene Alias:
__
Immunogen:
__
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Refrigerate (2 to 8°C)
Classification:
Monoclonal
Concentration:
__
Formulation:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ