BDB566365

TNF Rat anti-Mouse, Brilliant Violet 750, Clone: MP6-XT22, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB566365-Each-of-1 In Stock ₹ 33,197.28

BDB566365 - Each of 1

₹ 33,197.28

In Stock

Quantity

1

Base Price: ₹ 33,197.28

GST (18%): ₹ 5,975.51

Total Price: ₹ 39,172.79

Antigen

TNF

Clone

MP6-XT22

Conjugate

Brilliant Violet 750

Gene Alias

Tnf, Tnfa, TNF alpha, TNF-a, Tnfsf1a, Tnfsf2, TNFSF2, Cachectin, DIF

Immunogen

Recombinant Mouse TNF

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1

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Description

  • The MP6-XT22 antibody specifically TNF is produced by many activated cell types including monocytes, macrophages, astrocytes, granulocytes, mast cells, T and B lymphocytes, NK cells, keratinocytes, fibroblasts, adipocytes, and certain tumor cells
  • Activated cells express type II transmembrane TNF glycoproteins that associate as homotrimeric complexes
  • After enzymatic cleavage, the extracellular regions of membrane TNF are shed as soluble homotrimers
  • TNF is a potent multifunctional cytokine that can exert regulatory and cytotoxic effects on a wide range of normal lymphoid and non-lymphoid cells and tumor cells
  • Although TNF serves as a primary mediator in protective immune responses against microbial and viral pathogens, it can also drive systemic pathophysiologic responses including septic shock, cachexia and autoimmune diseases
  • Mouse TNF exerts its biological activities by binding and signaling through cell surface membrane Type I and Type II TNF Receptors (aka, TNFRI/CD120a and TNFRII/CD120b, respectively)
  • The antibody was conjugated to BD Horizon BV750 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 750nm
  • BD Horizon Brilliant BV750 can be excited by the violet laser (405 nm) and detected with a 750/30 nm filter with a 740 nm long pass
  • Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BV750 reagents
  • Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended
  • BV750

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Show Difference

Img

BD Biosciences

BDB566365

--


Antigen:
TNF

Clone:
MP6-XT22

Conjugate:
Brilliant Violet 750

Gene Alias:
Tnf, Tnfa, TNF alpha, TNF-a, Tnfsf1a, Tnfsf2, TNFSF2, Cachectin, DIF

Immunogen:
Recombinant Mouse TNF

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1

Img

BD Biosciences

BDB566366

--


Antigen:
IFN-γ

Clone:
XMG1.2

Conjugate:
Brilliant Violet 750

Gene Alias:
Ifg, Ifng, IFN-γ, IFN-g, IFN-gamma, Interferon gamma, Type II Interferon

Immunogen:
Mouse IFN-γ Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 κ

Img

BD Biosciences

BDB566373

--


Antigen:
IRF8

Clone:
U31-644

Conjugate:
PE

Gene Alias:
IRF-8, IRF8, ICSBP, H-ICSBP, ICSBP1

Immunogen:
Human IRF8 Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB566377

--


Antigen:
CD127

Clone:
A7R34

Conjugate:
Brilliant Violet 421

Gene Alias:
Interleukin-7 receptor alpha chain, IL-7R alpha, IL7RA, IL-7RA, IL-7Rα, Il7

Immunogen:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ