BDB611137
ROCK-I Mouse, Unlabeled, Clone: 46, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB611137-Each-of-1 | In Stock | ₹ 48,426.96 |
BDB611137 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,426.96
GST (18%): ₹ 8,716.853
Total Price: ₹ 57,143.813
Antigen
ROCK-I
Classification
Monoclonal
Concentration
250μg/mL
Description
ROKβ
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Applications
Western Blot
Clone
46
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Mouse ROCK-I aa. 906-1012
Quantity
150 μg
Research Discipline
Cell Biology
Target Species
Human, Mouse, Rat
Isotype
IgG1
Related Products
Description
- ROCK-I is a Rho-associated serine/threonine kinase isozyme that mediates RhoA-induced assembly of focal adhesions and actin stress fibers
- It contains an N-terminal kinase domain, a central 600 amino acid long coiled-coil region, a C-terminal pleckstrin homology region (PH) and a Cys-rich zinc finger motif
- The ROCK-I kinase domain is approximately 90% identical to that of ROCK-II
- ROCK-I binds GTP-bound Rho through a Rho-binding domain (RBD)
- As a result, the kinase activity of ROCK-I is moderately stimulated
- The ROCK isozymes regulate cell contractility through phosphorylation of the myosin light chain
- This effect results from either the inhibition of the myosin phosphatase or by direct phosphorylation of the myosin light chain, thus bypassing the myosin light chain kinase
- In addition, ROCK-I activates the ubiquitously expressed Na-H exchanger (NHE1) via a number of mechanisms including RhoA
- NHE1 may mediate ROCK-I-induced changes in the actin cytoskeleton
- Therefore, ROCK-I plays an important role in the regulation of focal adhesion and stress fiber formation
- Host Species: Mouse Clone: 46 Isotype: IgG1 Species Reactivity: Mouse Immunogen: Mouse ROCK-I aa
- 906-1012 Formula Weight [Chemical]: 160kDa Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: ROCK-I
Classification: Monoclonal
Concentration: 250μg/mL
Description: ROKβ
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 46
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse ROCK-I aa. 906-1012
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1
Antigen:
ROCK-I
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
ROKβ
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
46
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse ROCK-I aa. 906-1012
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1
Antigen: CD61
Classification: Monoclonal
Concentration: 250μg/mL
Description: Integrin β3 chain
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 1
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Integrin β3 aa. 592-712
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Antigen:
CD61
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
Integrin β3 chain
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
1
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Integrin β3 aa. 592-712
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Antigen: Thrombospondin-2
Classification: Monoclonal
Concentration: 250μg/mL
Description: TSP-2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 4
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Thrombospondin-2 aa. 173-295
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Mouse
Isotype: IgG1
Antigen:
Thrombospondin-2
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
TSP-2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
4
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Thrombospondin-2 aa. 173-295
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Mouse
Isotype:
IgG1
Antigen: Hic5
Classification: Monoclonal
Concentration: 250μg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Applications: Western Blot
Clone: 34
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse Hic-5 aa. 73-186
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1
Antigen:
Hic5
Classification:
Monoclonal
Concentration:
250μg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Applications:
Western Blot
Clone:
34
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse Hic-5 aa. 73-186
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1